Trial reportFrontiers in immunology2020
Iron Deficiency Anemia at Time of Vaccination Predicts Decreased Vaccine Response and Iron Supplementation at Time of Vaccination Increases Humoral Vaccine Response: A Birth Cohort Study and a Randomized Trial Follow-Up Study in Kenyan Infants.
Open access · goldAbstract readRandomized Controlled Trial
In one paragraph
Trial report in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens.EBioMedicine · 2022Pooled it
- Associations of maternal iron deficiency with malaria infection in a cohort of pregnant Papua New Guinean women.Malaria journal · 2022Trial
- Ferric carboxymaltose and SARS-CoV-2 vaccination-induced immunogenicity in kidney transplant recipients with iron deficiency: The COVAC-EFFECT randomized controlled trial.Frontiers in immunology · 2022Trial
- Review
- A Double-Edged Sword: Breast Milk-Derived Maternal Antibodies and Infant Vaccine Responses: A Narrative Review.Vaccines · 2026Review
- Host iron deficiency protects againstScience advances · 2026Article
- Dietary iron deficiency impairs effector function of memory T cells following influenza infection.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Association of plasma ferritin and plasma iron at time of vaccination with the immune response to SARS-CoV-2 vaccination: a longitudinal cohort study.Frontiers in immunology · 2026Article
- Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination.Gut microbes · 2025Review
- Iron deficiency and vaccine efficacy: A mini-review of immunological interplay and evidence across vaccine types.Human vaccines & immunotherapeutics · 2025Review
- Iron and the immune system.Nature reviews. Immunology · 2025Review
- Transferrin knockout reveals a tolerance phenotype against Piscirickettsia salmonis in Atlantic salmon phagocytes.Veterinary research · 2025Article
- Presetting CAR-T cells during ex vivo biomanufacturing.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Review
- Expression of salivary hepcidin and its inducer, interleukin 6 as well as type I interferons are significantly elevated in infants with poor oral rotavirus vaccine take in South Africa.Frontiers in immunology · 2025Article
- Mapping Community Vulnerability to reduced Vaccine Impact in Uganda and Kenya: A spatial Data-driven Approach.NIHR open research · 2025Article
- Iron, Hepcidin, and Immunity.Advances in experimental medicine and biology · 2025Review
- Why cells need iron: a compendium of iron utilisation.Trends in endocrinology and metabolism: TEM · 2024Review
- Early life stress and iron metabolism in developmental psychoneuroimmunology.Brain, behavior, & immunity - health · 2024Article
- How does geographical diversity shape vaccine efficacy?Clinical and experimental vaccine research · 2024Review
- Characterization of serum proteomic and inflammatory profiling at early stage of iron deficiency in weaned piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 9 institutions in 6 countries.
Nicole U StoffelDepartment of Health Sciences and Technology, Institute of Food, Nutrition and Health, Laboratory of Human Nutrition, ETH Zürich, Zurich, Switzerland.
Mary A UyogaDepartment of Health Sciences and Technology, Institute of Food, Nutrition and Health, Laboratory of Human Nutrition, ETH Zürich, Zurich, Switzerland.
Francis M MutukuDepartment of Environment and Health Sciences, Technical University Mombasa, Mombasa, Kenya.
Joe N FrostMRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
Edith MwasiPediatrics Department, Msambweni County Referral Hospital, Msambweni, Kenya.
Daniela PaganiniDepartment of Health Sciences and Technology, Institute of Food, Nutrition and Health, Laboratory of Human Nutrition, ETH Zürich, Zurich, Switzerland.
Fiona R M van der KlisCentre for Infectious Disease Control, National Institute for Public Health and Environment (RIVM), Bilthoven, Netherlands.
Indu J MalhotraCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
A Desiráe LaBeaudDivision of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, CA, United States.
Cristian RicciPediatric Epidemiology, Department of Pediatrics, Medical Faculty, Leipzig University, Leipzig, Germany.
Simon KaranjaDepartment of Medical Epidemiology, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Hal DrakesmithMRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
Charles H KingCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Michael B ZimmermannDepartment of Health Sciences and Technology, Institute of Food, Nutrition and Health, Laboratory of Human Nutrition, ETH Zürich, Zurich, Switzerland.
ETH Zurich · CHCenter for Global Health · USJomo Kenyatta University of Agriculture and Technology · KELeipzig University · DELucile Packard Children's Hospital · USMRC Human Immunology Unit · GBMRC Weatherall Institute of Molecular Medicine · GBNational Institute for Public Health and the Environment · NLTechnical University of Mombasa · KE
Funding
Medical Research Council MC_UU_00008/10
Abstract
PubMed holds no abstract for this paper.
Indexed as
Dietary SupplementsAnemia, Iron-DeficiencyAntibodies, BacterialAntibodies, ViralChild, PreschoolCohort StudiesDouble-Blind MethodFemaleFollow-Up StudiesHumansImmunity, HumoralImmunoglobulin GInfantInfant, NewbornIronMaleAntibodies, BacterialAntibodies, ViralImmunoglobulin GIronVaccinesanemiainfancyironiron deficiencyKenyaseroconversionvaccine response
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.