Evidence map›Paper›PMID 32754067›Full record

ArticleFrontiers in psychiatry2020

Dynamic Neuroimaging Biomarkers of Smoking in Young Smokers.

Ting Xue, Fang Dong, Ruoyan Huang, Zhanlong Tao, Jun Tang, Yongxin Cheng, Mi Zhou, Yiting Hu, Xiaojian Li, Dahua Yu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. [Dynamic alterations in regional brain activity associated with bipolar disorder and smoking status].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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  3. Grey matter morphometry in young adult e-cigarette users, tobacco cigarette users & non-using controls.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
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  8. Early disturbance of dynamic synchronization and neurovascular coupling in cognitively normal Parkinson's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Ting XueSchool of Science, Inner Mongolia University of Science and Technology, Baotou, China.
Fang DongInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Ruoyan HuangInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Zhanlong TaoSchool of Science, Inner Mongolia University of Science and Technology, Baotou, China.
Jun TangSchool of Science, Inner Mongolia University of Science and Technology, Baotou, China.
Yongxin ChengInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Mi ZhouInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Yiting HuInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Xiaojian LiInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Dahua YuInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Haitao JuDepartment of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Kai YuanInner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
Inner Mongolia University of Science and Technology · CNInner Mongolia Medical University · CNXidian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine potential changes in the dynamic characteristics of regional neural activity in young smokers and to detect whether the changes were associated with smoking behavior.

methodsThe dynamic regional homogeneity (dReHo) and dynamic amplitude of low-frequency fluctuations (dALFF) in 40 young smokers and 42 nonsmokers were compared. Correlation analyses were also performed between dReHo and dALFF in areas showing group differences and smoking behavior [e.g., the Fagerström Test for Nicotine dependence (FTND) scores and pack-years].

resultsSignificantly differences in dReHo variability were observed in the inferior frontal gyrus (IFG), superior frontal gyrus (SFG), medial frontal gyrus (MFG), insula, cuneus, postcentral gyrus, inferior semi-lunar lobule, orbitofrontal gyrus, and inferior temporal gyrus (ITG). Young smokers also showed significantly increased dALFF variability in the anterior cingulate cortex (ACC) and ITG. Furthermore, a significant positive correlation was found between dALFF variability in the ACC and the pack-years; whereas a significant negative correlation between dReHo variability in the IFG and the FTND scores was found in young smokers.

conclusionThe pattern of resting state regional neural activity variability was different between young smokers and nonsmokers. Dynamic regional indexes might be a novel neuroimaging biomarker of smoking behavior in young smokers.

Indexed as

amplitude of low-frequency fluctuation (ALFF)dynamicregional homogeneity (ReHo)resting-state functional magnetic resonance imaging (rs-fMRI)young smokers

Identifiers

PMID32754067
PMCPMC7367415
OpenAlexW3041928548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.