Evidence map›Paper›PMID 32753867›Full record

ArticleInternational journal of nanomedicine2020

Assessment of Gold-Coated Iron Oxide Nanoparticles as Negative T2 Contrast Agent in Small Animal MRI Studies.

Stefania D Iancu, Camelia Albu, Liviu Chiriac, Remus Moldovan, Andrei Stefancu, Vlad Moisoiu, Vasile Coman, Laszlo Szabo, Nicolae Leopold, Zoltán Bálint

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Long-Term Biodistribution of FeInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Stimuli-Responsive Materials for Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  5. Nanotheranostics: A Cutting-edge Technology for Cancer Management.Current pharmaceutical biotechnology · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Stefania D IancuIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.
Camelia AlbuIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.ORCID 0000-0001-7224-9778
Liviu ChiriacIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.ORCID 0000-0002-1416-4220
Remus MoldovanIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.
Andrei StefancuIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.ORCID 0000-0002-1455-2055
Vlad MoisoiuIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.
Vasile ComanIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.
Laszlo SzaboIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.ORCID 0000-0002-7038-8317
Nicolae LeopoldIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.ORCID 0000-0002-2174-8064
Zoltán BálintIMOGEN Medical Research Institute, County Clinical Emergency Hospital, Cluj-Napoca 400012, Romania.
Clinical Emergency Hospital Bucharest · ROIuliu Hațieganu University of Medicine and Pharmacy · ROUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMagnetic resonance imaging (MRI) contrast agents are pharmaceuticals that enable a better visualization of internal body structures. In this study, we present the synthesis, MRI signal enhancement capabilities, in vitro as well as in vivo cytotoxicity results of gold-coated iron oxide nanoparticles (Fe

methodsFe

resultsStable Fe

conclusionThe obtained stable, gold covered, iron oxide nanoparticles with reduced cytotoxicity, gave a negative T

Indexed as

Magnetic Resonance ImagingAnimalsCell SurvivalContrast MediaEndocytosisFerric CompoundsGoldInflammationMaleMetal NanoparticlesRats, WistarX-Ray DiffractionContrast MediaFerric Compoundsferric oxideGoldcytotoxicityD407 cellsgold-coated iron oxide nanoparticleshistopathologyMRI contrast agentrats

Identifiers

PMID32753867
PMCPMC7355080
OpenAlexW3039172568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.