Evidence map›Paper›PMID 32753716›Full record

ArticleScientific reports2020

Uncovering a possible role of reactive oxygen species in magnetogenetics.

Matthew I Brier, Jordan W Mundell, Xiaofei Yu, Lichao Su, Alexander Holmann, Jessica Squeri, Baolin Zhang, Sarah A Stanley, Jeffrey M Friedman, Jonathan S Dordick

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Electrophysiological Mechanisms and Validation of Ferritin-Based Magnetogenetics for Remote Control of Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Review
  7. Article
  8. Magnetogenetic cell activation using endogenous ferritin.bioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Enhancing ROS-Inducing Nanozyme through Intraparticle Electron Transport.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  11. Review
  12. Applications of synthetic biology in medical and pharmaceutical fields.Signal transduction and targeted therapy · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Matthew I BrierDepartment of Chemical and Biological Engineering, and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Jordan W MundellDepartment of Chemical and Biological Engineering, and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Xiaofei YuLaboratory of Molecular Genetics, Rockefeller University, New York, NY, 10065, USA.
Lichao SuState Key Laboratory Breeding Base of Nonferrous Metals and Specific Materials Processing, College of Material Science and Engineering, Guilin University of Technology, Jian Gan Road 12, Guilin, 541004, China.
Alexander HolmannDepartment of Chemical and Biological Engineering, and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Jessica SqueriDepartment of Chemical and Biological Engineering, and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Baolin ZhangState Key Laboratory Breeding Base of Nonferrous Metals and Specific Materials Processing, College of Material Science and Engineering, Guilin University of Technology, Jian Gan Road 12, Guilin, 541004, China.
Sarah A StanleyDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine At Mount Sinai, New York, NY, 10029, USA.
Jeffrey M FriedmanLaboratory of Molecular Genetics, Rockefeller University, New York, NY, 10065, USA.
Jonathan S DordickDepartment of Chemical and Biological Engineering, and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA. dordick@rpi.edu.
Rensselaer Polytechnic Institute · USGuilin University of Technology · CNFudan University · CNIcahn School of Medicine at Mount Sinai · USRockefeller University · US

Funding

Remote Electromagnetic Control of Neural Activity for Treatment of Parkinson's DiseaseR01NS097184 · NINDS · ROCKEFELLER UNIVERSITY · PI DORDICK, JONATHAN S., FRIEDMAN, JEFFREY M · 2016 to 2020
$3.4M
The Alzheimer's Disease Clinical and Translational Research (ADCTR) Training ProgramT32AG057464 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI WANG, CHUNYU · 2017 to 2021
$1.6M
Remote regulation of neural activityU01MH105941 · NIMH · ROCKEFELLER UNIVERSITY · PI STANLEY, SARAH AMY · 2014 to 2016
$1.2M
Remote Modulation of the Peripheral Nervous SystemOT2OD024912 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI STANLEY, SARAH AMY · 2017 to 2019
$1.1M
Predoctoral Training Program for Alzheimer’s Disease at the Interface of Data Science, Engineering and BiologyT32AG078123 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI Chunyu Wang · 2023 to 2026
$974k
NIA NIH HHS T32 AG057464NIA NIH HHS T32 AG078123NIH HHS OT2 OD024912NIMH NIH HHS U01 MH105941NINDS NIH HHS R01 NS097184
6 · The paper itself

Abstract

Recent reports have shown that intracellular, (super)paramagnetic ferritin nanoparticles can gate TRPV1, a non-selective cation channel, in a magnetic field. Here, we report the effects of differing field strength and frequency as well as chemical inhibitors on channel gating using a Ca

Indexed as

Magnetic FieldsAnimalsFerritinsHEK293 CellsHumansRatsReactive Oxygen SpeciesTRPV Cation ChannelsFerritinsReactive Oxygen SpeciesTrpv1 protein, ratTRPV Cation Channels

Identifiers

PMID32753716
PMCPMC7403421
OpenAlexW3047474711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.