ArticleCommunications biology2020
Genomic analyses of a livestock pest, the New World screwworm, find potential targets for genetic control programs.
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 52 citations in OpenAlex.
- Genome sequencing and multi-stage, blood-feeding, and tissue-specific transcriptome atlas of the Rocky Mountain wood tick provide a critical resource for this vector.Insect biochemistry and molecular biology · 2026Article
- Of cattle and humans: A narrative review on the re-emergence of the New World screwworm (Cochliomyia hominivorax) and its threat to human health.PLoS neglected tropical diseases · 2026Review
- Validation of a molecular workflow for Cochliomyia hominivorax (New World screwworm) identification in field samples.Scientific reports · 2026Article
- Haplotype-resolved genome assemblies for the New World screwworm, Cochliomyia hominivorax (Diptera: Calliphoridae), using the trio binning approach.G3 (Bethesda, Md.) · 2026Article
- Genome sequencing and multi-stage, blood-feeding, and tissue-specific transcriptome atlas of the Rocky Mountain wood tick provide a critical resource for this vector.bioRxiv : the preprint server for biology · 2026Article
- Improving the sex-specificity of a conditional female lethal system for genetic biocontrol of the New World screwworm, Cochliomyia hominivorax.Scientific reports · 2025Article
- Tetracycline has no long-term effects on gut physiology and microbiome of the new world screwworm, Cochliomyia hominivorax, which has positive implications for transgenic male-only rearing systems.G3 (Bethesda, Md.) · 2025Article
- Demographic and historical processes influencing Cochliomyia hominivorax (Diptera: Calliphoridae) population structure across South America.Parasites & vectors · 2025Article
- Shifted levels of sleep and activity during the night as mechanisms underlying ectoparasite resistance.Npj biological timing and sleep · 2025Article
- Antennal transcriptome analysis reveals sensory receptors potentially associated with host detection in the livestock pest Lucilia cuprina.Parasites & vectors · 2024Article
- Transcriptomic profiling of different developmental stages reveals parasitic strategies of Wohlfahrtia magnifica, a myiasis-causing flesh fly.BMC genomics · 2024Article
- Diaci v3.0: chromosome-level assembly, de novo transcriptome, and manual annotation of Diaphorina citri, insect vector of Huanglongbing.GigaScience · 2024Article
- Article
- A chromosomal-scale reference genome of the New World Screwworm, Cochliomyia hominivorax.DNA research : an international journal for rapid publication of reports on genes and genomes · 2023Article
- Genomic insights into evolution and control of Wohlfahrtia magnifica, a widely distributed myiasis-causing fly of warm-blooded vertebrates.Molecular ecology resources · 2022Article
- Abundances of transfer RNA modifications and transcriptional levels of tRNA-modifying enzymes are sex-associated in mosquitoes.Insect biochemistry and molecular biology · 2022Article
- The genome sequence of the avian vampire fly (Philornis downsi), an invasive nest parasite of Darwin's finches in Galápagos.G3 (Bethesda, Md.) · 2022Article
- Disruption of the odorant coreceptor Orco impairs foraging and host finding behaviors in the New World screwworm fly.Scientific reports · 2021Article
- An early female lethal system of the New World screwworm, Cochliomyia hominivorax, for biotechnology-enhanced SIT.BMC genetics · 2020Article
- Physiological and molecular correlates of the screwworm fly attraction to wound and animal odors.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 2 countries.
Funding
Abstract
The New World Screwworm fly, Cochliomyia hominivorax, is a major pest of livestock in South America and Caribbean. However, few genomic resources have been available for this species. A genome of 534 Mb was assembled from long read PacBio DNA sequencing of DNA from a highly inbred strain. Analysis of molecular evolution identified 40 genes that are likely under positive selection. Developmental RNA-seq analysis identified specific genes associated with each stage. We identify and analyze the expression of genes that are likely important for host-seeking behavior (chemosensory), development of larvae in open wounds in warm-blooded animals (heat shock protein, immune response) and for building transgenic strains for genetic control programs including gene drive (sex determination, germline). This study will underpin future experiments aimed at understanding the parasitic lifestyle of the screwworm fly and greatly facilitate future development of strains for efficient systems for genetic control of screwworm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.