Evidence map›Paper›PMID 32753590›Full record

ArticleScientific reports2020

Effect of 6p21 region on lung function is modified by smoking: a genome-wide interaction study.

Boram Park, Jaehoon An, Wonji Kim, Hae Yeon Kang, Sang Baek Koh, Bermseok Oh, Keum Ji Jung, Sun Ha Jee, Woo Jin Kim, Michael H Cho and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Genetics of chronic respiratory disease.Nature reviews. Genetics · 2024
    Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Boram ParkDepartment of Public Health Sciences, Seoul National University, Seoul, South Korea.
Jaehoon AnDepartment of Public Health Sciences, Seoul National University, Seoul, South Korea.
Wonji KimInterdisciplinary Program of Bioinformatics, Seoul National University, Seoul, South Korea.
Hae Yeon KangDepartment of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, South Korea.
Sang Baek KohDepartment of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
Bermseok OhDepartment of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, South Korea.
Keum Ji JungInstitute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea.
Sun Ha JeeInstitute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea.
Woo Jin KimDepartment of Internal Medicine and Environmental Health Center, Kangwon National University Hospital, School of Medicine, Kangwon University, Chuncheon, South Korea.
Michael H ChoChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Edwin K SilvermanChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Taesung ParkInterdisciplinary Program of Bioinformatics, Seoul National University, Seoul, South Korea. tspark@stats.snu.ac.kr.
Sungho WonDepartment of Public Health Sciences, Seoul National University, Seoul, South Korea. sunghow@gmail.com.
Seoul National University · KRYonsei University · KRBrigham and Women's Hospital · USHarvard University · USKorea Health Promotion Institute · KRKyung Hee University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD); however, more than 25% of COPD patients are non-smokers, and gene-by-smoking interactions are expected to affect COPD onset. We aimed to identify the common genetic variants interacting with pack-years of smoking on FEV

Indexed as

Genome-Wide Association StudyCase-Control StudiesChromosomes, Human, Pair 6Cohort StudiesFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPolymorphism, Single NucleotidePulmonary Disease, Chronic ObstructiveQuantitative Trait LociSmoking

Identifiers

PMID32753590
PMCPMC7403370
OpenAlexW3047541683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.