Evidence map›Paper›PMID 32753578›Full record

Trial reportScientific reports2020

Development of digital breast tomosynthesis and diffuse optical tomography fusion imaging for breast cancer detection.

Eun Young Chae, Hak Hee Kim, Sohail Sabir, Yejin Kim, Hyeongseok Kim, Sungho Yoon, Jong Chul Ye, Seungryong Cho, Duchang Heo, Kee Hyun Kim and 2 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

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  8. Evolution of tomosynthesis.Journal of medical imaging (Bellingham, Wash.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Eun Young ChaeDepartment of Radiology, Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-Gil, Songpa-Gu, Seoul, 05505, South Korea.
Hak Hee KimDepartment of Radiology, Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-Gil, Songpa-Gu, Seoul, 05505, South Korea. hhkim@amc.seoul.kr.
Sohail SabirDepartment of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea.
Yejin KimDepartment of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea.
Hyeongseok KimDepartment of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea.
Sungho YoonDepartment of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea.
Jong Chul YeDepartment of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea.
Seungryong ChoDepartment of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea.
Duchang HeoKorea Electrotechnology Research Institute (KERI), 111, Hanggaul-ro, Sangnok-gu, Ansan, 15588, South Korea.
Kee Hyun KimKorea Electrotechnology Research Institute (KERI), 111, Hanggaul-ro, Sangnok-gu, Ansan, 15588, South Korea.
Young Min BaeKorea Electrotechnology Research Institute (KERI), 111, Hanggaul-ro, Sangnok-gu, Ansan, 15588, South Korea.
Young-Wook ChoiKorea Electrotechnology Research Institute (KERI), 111, Hanggaul-ro, Sangnok-gu, Ansan, 15588, South Korea.
Korea Advanced Institute of Science and Technology · KRKorea Electrotechnology Research Institute · KRUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse optical tomography (DOT) non-invasively measures the functional characteristics of breast lesions using near infrared light to probe tissue optical properties. This study aimed to evaluate a new digital breast tomosynthesis (DBT)/DOT fusion imaging technique and obtain preliminary data for breast cancer detection. Twenty-eight women were prospectively enrolled and underwent both DBT and DOT examinations. DBT/DOT fusion imaging was created after acquisition of both examinations. Two breast radiologists analyzed DBT and DOT images independently, and then finally evaluated the fusion images. The diagnostic performance of each reading session was compared and interobserver agreement was assessed. The technical success rate was 96.4%, with one failure due to an error during DOT data storage. Among the 27 women finally included in the analysis, 13 had breast cancer. The areas under the receiver operating characteristic curve (AUCs) for DBT were 0.783 and 0.854 for readers 1 and 2, respectively. DOT showed comparable diagnostic performance to DBT for both readers. The AUCs were significantly improved (P = 0.004) when the DBT/DOT fusion images were used. Interobserver agreements were highest for the DBT/DOT fusion images. In conclusion, this study suggests that DBT/DOT fusion imaging technique appears to be a promising tool for breast cancer diagnosis.

Indexed as

Image Processing, Computer-AssistedMammographyTomography, OpticalAdultBreast NeoplasmsFemaleHumansMiddle Aged

Identifiers

PMID32753578
PMCPMC7403423
OpenAlexW3047454941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.