Evidence map›Paper›PMID 32753576›Full record

ArticleScientific reports2020

Differential effects of ethanol on behavior and GABA

Alexander C Goodman, Ryan Y Wong

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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  10. Zebrafish (Ecology and evolution · 2024
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  11. Zebrafish (bioRxiv : the preprint server for biology · 2024
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  14. Early-Stage High-Concentration Thiacloprid Exposure Induced Persistent Behavioral Alterations in Zebrafish.International journal of environmental research and public health · 2022
    Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander C GoodmanDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, 68182, USA. alexander.c.goodman@gmail.com.
Ryan Y WongDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, 68182, USA. rwong@unomaha.edu.
University of Nebraska at Omaha · US

Funding

Neural and Molecular Mechanisms in Stress CopingR15MH113074 · NIMH · UNIVERSITY OF NEBRASKA OMAHA · PI WONG, RYAN YING · 2017 to 2017
$346k
NIMH NIH HHS R15 MH113074
6 · The paper itself

Abstract

Variation in stress responses between individuals are linked to factors ranging from stress coping styles to sensitivity of neurotransmitter systems. Many anxiolytic compounds (e.g. ethanol) can increase stressor engagement through modulation of neurotransmitter systems and are used to investigate stress response mechanisms. There are two alternative suites of correlated behavioral and physiological responses to stressors (stress coping styles) that differ in exploration tendencies: proactive and reactive stress coping styles. By chronically treating individuals differing in stress coping style with ethanol, a GABA-acting drug, we assessed the role of the GABAergic system on the behavioral stress response. Specifically, we investigated resulting changes in stress-related behavior (i.e. exploratory behavior) and whole-brain GABA

Indexed as

Adaptation, PsychologicalAnimalsBehavior, AnimalDose-Response Relationship, DrugEthanolGene Expression RegulationReceptors, GABA-AStress, PsychologicalTime FactorsZebrafishEthanolReceptors, GABA-A

Identifiers

PMID32753576
PMCPMC7403336
OpenAlexW3047591070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.