Evidence map›Paper›PMID 32753543›Full record

ArticleJournal for immunotherapy of cancer2020

Is there a link between very early changes of primary and secondary lymphoid organs in

Ferdinand Seith, Andrea Forschner, Benjamin Weide, Brigitte Gückel, Martin Schwartz, Johannes Schwenck, Ahmed E Othman, Matthias Fenchel, Claus Garbe, Konstantin Nikolaou and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. 3'-deoxy-3'-EJNMMI research · 2025
    Article
  4. The Combined Prognostic Value ofCancer medicine · 2025
    Article
  5. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Theranostics · 2023
    Article
  11. Article
  12. MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Ferdinand SeithDiagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany ferdinand.seith@med.uni-tuebingen.de.ORCID 0000-0002-9696-2954
Andrea ForschnerDermatology, Eberhard Karls University Tübingen, Tübingen, Baden-Württemberg, Germany.ORCID 0000-0002-6185-4945
Benjamin WeideDermatology, Eberhard Karls University Tübingen, Tübingen, Baden-Württemberg, Germany.
Brigitte GückelDiagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany ferdinand.seith@med.uni-tuebingen.de.
Martin SchwartzSection on Experimental Radiology, Eberhard Karls University Tübingen, Tubingen, Germany.
Johannes SchwenckNuclear Medicine and Clinical Molecular Imaging, Eberhard Karls University Tübingen, Tubingen, Baden-Württemberg, Germany.
Ahmed E OthmanDiagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany ferdinand.seith@med.uni-tuebingen.de.
Matthias FenchelDiagnostic Imaging, Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Bayern, Germany.
Claus GarbeDermatology, Eberhard Karls University Tübingen, Tübingen, Baden-Württemberg, Germany.
Konstantin NikolaouDiagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany ferdinand.seith@med.uni-tuebingen.de.
Nina SchwenzerDiagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany ferdinand.seith@med.uni-tuebingen.de.
Christian la FougèreNuclear Medicine and Clinical Molecular Imaging, Eberhard Karls University Tübingen, Tubingen, Baden-Württemberg, Germany.
Christina PfannenbergDiagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany ferdinand.seith@med.uni-tuebingen.de.
University of Tübingen · DESiemens (Germany) · DESiemens Healthineers (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Response assessment or prediction to checkpoint inhibitor therapy (CIT) is an unsolved problem in current routine diagnostics of patients with melanoma. Here, we evaluated very early changes of primary and secondary lymphoid organs under CIT in multiparametric [

Indexed as

FemaleFluorodeoxyglucose F18HumansImmune Checkpoint InhibitorsMalePositron Emission Tomography Computed TomographyProspective StudiesFluorodeoxyglucose F18Immune Checkpoint InhibitorsCTLA-4 antigenmelanomaprogrammed cell death 1 receptor

Identifiers

PMID32753543
PMCPMC7406110
OpenAlexW3046964957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.