Evidence map›Paper›PMID 32753528›Full record

ArticleLife science alliance2020

Sam68 splicing regulation contributes to motor unit establishment in the postnatal skeletal muscle.

Elisa De Paola, Laura Forcina, Laura Pelosi, Simona Pisu, Piergiorgio La Rosa, Eleonora Cesari, Carmine Nicoletti, Luca Madaro, Neri Mercatelli, Filippo Biamonte and 8 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. NMJ-related diseases beyond the congenital myasthenic syndromes.Frontiers in cell and developmental biology · 2023
    Review
  4. Article
  5. Article
  6. Cancers · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Elisa De PaolaDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico," Rome, Italy.
Laura ForcinaLaboratory Affiliated to Istituto Pasteur-Fondazione Cenci Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy.
Laura PelosiLaboratory Affiliated to Istituto Pasteur-Fondazione Cenci Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-3964-8157
Simona PisuLaboratory Affiliated to Istituto Pasteur-Fondazione Cenci Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy.
Piergiorgio La RosaIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy.ORCID 0000-0002-9723-2363
Eleonora CesariIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy.
Carmine NicolettiLaboratory Affiliated to Istituto Pasteur-Fondazione Cenci Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy.
Luca MadaroInstitute of Human Anatomy and Cell Biology, Catholic University of the Sacred Heart, Rome, Italy.
Neri MercatelliDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico," Rome, Italy.
Filippo BiamonteInstitute of Biochemistry and Clinical Biochemistry, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Annalisa NobiliIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy.
Marcello D'AmelioIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy.
Marco De BardiIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy.ORCID 0000-0001-8217-970X
Elisabetta VolpeIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy.
Daniela CaporossiDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico," Rome, Italy.
Claudio SetteIRCCS (Institute for Treatment and Research) Fondazione Santa Lucia, Rome, Italy claudio.sette@unicatt.it.
Antonio MusaròLaboratory Affiliated to Istituto Pasteur-Fondazione Cenci Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy antonio.musaro@uniroma1.it.
Maria Paola ParonettoDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico," Rome, Italy mariapaola.paronetto@uniroma4.it.ORCID 0000-0001-5324-0903
Istituto Pasteur · ITForo Italico University of Rome · ITFondazione Santa Lucia · ITUniversità Cattolica del Sacro Cuore · ITUniversità Campus Bio-Medico · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-binding proteins orchestrate the composite life of RNA molecules and impact most physiological processes, thus underlying complex phenotypes. The RNA-binding protein Sam68 regulates differentiation processes by modulating splicing, polyadenylation, and stability of select transcripts. Herein, we found that

Indexed as

Adaptor Proteins, Signal TransducingAlternative SplicingAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutMotor NeuronsMuscle, SkeletalNeuromuscular JunctionRNA-Binding ProteinsRNA SplicingSynapsesAdaptor Proteins, Signal TransducingKhdrbs1 protein, mouseRNA-Binding Proteins

Identifiers

PMID32753528
PMCPMC7409371
OpenAlexW3046982240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.