Evidence map›Paper›PMID 32753494›Full record

ArticlemBio2020

Bacterial Evolution in High-Osmolarity Environments.

Spencer Cesar, Maya Anjur-Dietrich, Brian Yu, Ethan Li, Enrique Rojas, Norma Neff, Tim F Cooper, Kerwyn Casey Huang

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  6. Antimicrobial efficacy of 45S5 and borosilicate bioglasses against multidrug-resistant bacteria: an in vitro assay.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  8. UnveilingFoods (Basel, Switzerland) · 2025
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  9. First report on the long-term viability ofJournal of water and health · 2024
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  10. Evolution of pH-sensitive transcription termination inProceedings of the National Academy of Sciences of the United States of America · 2024
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  18. GABA Production by Human IntestinalFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Spencer Cesar *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Maya Anjur-Dietrich *Department of Bioengineering, Stanford University, Stanford, California, USA.
Brian YuChan Zuckerberg Biohub, San Francisco, California, USA.
Ethan LiDepartment of Bioengineering, Stanford University, Stanford, California, USA.
Enrique RojasDepartment of Bioengineering, Stanford University, Stanford, California, USA.
Norma NeffChan Zuckerberg Biohub, San Francisco, California, USA.
Tim F CooperDepartment of Biology and Biochemistry, University of Houston, Houston, Texas, USA.
Kerwyn Casey HuangDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA kchuang@stanford.edu.ORCID 0000-0002-8043-8138
Stanford University · USChan Zuckerberg Initiative (United States) · USUniversity of Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria must maintain a cytosolic osmolarity higher than that of their environment in order to take up water. High-osmolarity environments therefore present formidable stress to bacteria. To explore the evolutionary mechanisms by which bacteria adapt to high-osmolarity environments, we selected

Indexed as

Evolution, MolecularMutationAdaptation, PhysiologicalColony Count, MicrobialCulture MediaEnvironmentEscherichia coliOsmolar ConcentrationPhenotypeStress, PhysiologicalCulture Mediacell morphologycell shapeosmolytesosmotic adaptationprolinesorbitolstress responsesucrose

Identifiers

PMID32753494
PMCPMC7407084
OpenAlexW3047205088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.