Evidence map›Paper›PMID 32753389›Full record

ArticleGenetics2020

A Novel Mechanism for Activation of Myosin Regulatory Light Chain by Protein Kinase C-Delta in

Pooneh Vaziri, Danielle Ryan, Christopher A Johnston, Richard M Cripps

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pooneh VaziriDepartment of Biology, San Diego State University, San Diego, California 92182.
Danielle RyanDepartment of Biology, San Diego State University, San Diego, California 92182.
Christopher A JohnstonDepartment of Biology, University of New Mexico, Albuquerque, New Mexico 87131.
Richard M CrippsDepartment of Biology, San Diego State University, San Diego, California 92182 rcripps@sdsu.edu.ORCID 0000-0001-6565-285X
San Diego State University · USUniversity of New Mexico · US

Funding

GENETIC REGULATION OF MUSCLE FIBER DIVERSITYR01GM061738 · NIGMS · UNIVERSITY OF NEW MEXICO · PI CRIPPS, RICHARD MATTHEW · 2001 to 2022
$6.4M
COBRE Center for Evolutionary and Theoretical ImmunologyP20GM103452 · NIGMS · UNIVERSITY OF NEW MEXICO · PI LOKER, ERIC SAMUEL · 2012 to 2013
$4.2M
Cytoskeletal-mediated regulation of spindle orientationR01GM108756 · NIGMS · UNIVERSITY OF NEW MEXICO · PI JOHNSTON, CHRISTOPHER A. · 2014 to 2018
$1.4M
NIGMS NIH HHS P20 GM103452NIGMS NIH HHS R01 GM061738NIGMS NIH HHS R01 GM108756
6 · The paper itself

Abstract

Myosin is an essential motor protein, which in muscle is comprised of two molecules each of myosin heavy-chain (MHC), the essential or alkali myosin light-chain 1 (MLC1), and the regulatory myosin light-chain 2 (MLC2). It has been shown previously that MLC2 phosphorylation at two canonical serine residues is essential for proper flight muscle function in

Indexed as

AnimalsCardiac MyosinsDrosophila melanogasterHumansMyosin Light ChainsPhenotypePhosphorylationProtein Kinase C-deltaProtein Processing, Post-TranslationalSarcomeresCardiac Myosinsmyosin light chain 2Myosin Light ChainsProtein Kinase C-deltaDrosophilaflight musclemuscle maturationmyosin light chainphosphorylationPKC delta

Identifiers

PMID32753389
PMCPMC7463289
OpenAlexW3047197573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.