ArticleReproductive biomedicine online2020
Population implications of cessation of IVF during the COVID-19 pandemic.
Article in Reproductive biomedicine online, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Impact of Coronavirus Disease 2019 on Fertility: An Integrative Review.The International journal of health planning and management · 2025Review
- Increased adverse pregnancy outcomes among decreased assisted reproductions during the COVID-19 pandemic: insights from a birth cohort study in Southwest China.BMC pregnancy and childbirth · 2024Article
- Experiences of patients undergoing IVF treatment during the COVID-19 pandemic.JBRA assisted reproduction · 2023Article
- Embryo development, pregnancy and live birth outcomes following IVF treatment were not compromised during the COVID-19 pandemic.Journal of assisted reproduction and genetics · 2023Article
- SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023Review
- Self-Monitoring of Urinary Hormones in Combination with Telemedicine - a Timely Review and Opinion Piece in Medically Assisted Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- Expectant Management Before In vitro Fertilization in Women Aged 39 or Above and Unexplained Infertility Does Not Decrease Live Birth Rates Compared to Immediate Treatment.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- Obstetric interventions and pregnancy outcomes during the COVID-19 pandemic in England: A nationwide cohort study.PLoS medicine · 2022Article
- Use of Electronic Medical Records to Estimate Changes in Pregnancy and Birth Rates During the COVID-19 Pandemic.JAMA network open · 2021Article
- The Impact of the COVID-19 Pandemic on Pregnancy Planning Behaviors.Women's health reports (New Rochelle, N.Y.) · 2021Article
- The impact of Covid-19 on infertility services and future directions.Reproduction & fertility · 2020Article
- Resuming Assisted Reproduction Services during COVID-19 Pandemic: An Initial Indian Experience.Journal of human reproductive sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
research questionDiscontinuation of IVF cycles has been part of the radical transformation of healthcare provision to enable reallocation of staff and resources to deal with the COVID-19 pandemic. This study sought to estimate the impact of cessation of treatment on individual prognosis and US population live birth rates.
designData from 271,438 ovarian stimulation UK IVF cycles was used to model the effect of age as a continuous, yet non-linear, function on cumulative live birth rate. This model was recalibrated to cumulative live birth rates reported for the 135,673 stimulation cycles undertaken in the USA in 2016, with live birth follow-up to October 2018. The effect of a 1-month, 3-month and 6-month shutdown in IVF treatment was calculated as the effect of the equivalent increase in a woman's age, stratified by age group.
resultsThe average reduction in cumulative live birth rate would be 0.3% (95% confidence interval [CI] 0.3-0.3), 0.8% (95% CI 0.8-0.8) and 1.6% (95% CI 1.6-1.6) for 1-month, 3-month and 6-month shutdowns. This corresponds to a reduction of 369 (95% CI 360-378), 1098 (95% CI 1071-1123) and 2166 (95% CI 2116-2216) live births in the cohort, respectively. Th e greatest contribution to this reduction was from older mothers.
conclusionsThe study demonstrated that the discontinuation of fertility treatment for even 1 month in the USA could result in 369 fewer women having a live birth, due to the increase in patients' age during the shutdown. As a result of reductions in cumulative live birth rate, more cycles may be required to overcome infertility at individual and population levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.