ReviewThe Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques2021
Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic.
Review in The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
105 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Genome-wide association study meta-analysis uncovers novel genetic variants associated with olfactory dysfunction.BMC genomic data · 2025Pooled it
- Neuroinflammatory disorders of the central nervous system associated with monkeypox virus: a systematic review and call to action.BMC medicine · 2025Pooled it
- Late neurological consequences of SARS-CoV-2 infection: New challenges for the neurologist.Frontiers in neuroscience · 2023Pooled it
- The Mental Health of Caregivers and Their Patients With Dementia During the COVID-19 Pandemic: A Systematic Review.Frontiers in psychology · 2021Pooled it
- Machine Learning and Deep Learning Frameworks for Human-Virus Protein-Protein Interaction Prediction: Emerging Architectures, Methods, Benchmarks, and Challenges.International journal of molecular sciences · 2026Review
- Referral patterns surrounding the COVID-19 pandemic to a child and adolescent mental health clinic in Gauteng, South Africa.Frontiers in psychiatry · 2026Article
- The Search for Disease Modification in Parkinson's Disease-A Review of the Literature.Life (Basel, Switzerland) · 2025Review
- Sciatic Nerve Neuropathy Secondary to Sacral Pressure Ulcer Following COVID-19: A Case Report.Cureus · 2025Article
- Significance of Neurological Manifestations and Their Association With Clinical Outcomes in Hospitalized COVID-19 Patients in Bandar Abbas, Iran: A Cross-Sectional Study.Health science reports · 2025Article
- COVID-19 in patients with severe mental illness: An analysis of in-patients at a psychiatric hospital in Cape Town.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025Article
- Neuropsychiatric symptoms cluster as primary drivers of Long COVID complexity: a South Texas retrospective cohort study.Frontiers in neurology · 2025Article
- Fear and Impact of COVID-19 Among Post-Infected Adults: Types and Associations with Quality of Life and Post-Traumatic Stress Symptoms.Journal of epidemiology and global health · 2024Article
- Implications of COVID-19 in Parkinson's disease: the purinergic system in a therapeutic-target perspective to diminish neurodegeneration.Purinergic signalling · 2024Review
- Clinical outcomes of patients with seizure admitted for COVID-19: Findings from the Philippine CORONA study.Heliyon · 2024Article
- Long COVID-19 Enigma: Unmasking the Role of Distinctive Personality Profiles as Risk Factors.Journal of clinical medicine · 2024Article
- Unmasking the long-term effects: unravelling neuropsychiatric and neurological consequences of COVID-19.Annals of medicine and surgery (2012) · 2024Review
- Frequency and risk factors of psychological distress among individuals with epilepsy before and during the outbreak of the SARS-CoV-2 Omicron variant in China: an online questionnaire survey.Acta epileptologica · 2024Article
- Acute transverse myelitis (ATM) associated with COVID 19 infection and vaccination: A case report and literature review.AIMS neuroscience · 2024Article
- Addressing Long COVID Sequelae and Neurocovid: Neuropsychological Scenarios and Neuroimaging Findings.Advances in experimental medicine and biology · 2024Review
- Visual evoked potential abnormalities in patients with COVID-19.Revista da Associacao Medica Brasileira (1992) · 2024Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlbeit primarily a disease of respiratory tract, the 2019 coronavirus infectious disease (COVID-19) has been found to have causal association with a plethora of neurological, neuropsychiatric and psychological effects. This review aims to analyze them with a discussion of evolving therapeutic recommendations.
methodsPubMed and Google Scholar were searched from 1 January 2020 to 30 May 2020 with the following key terms: "COVID-19", "SARS-CoV-2", "pandemic", "neuro-COVID", "stroke-COVID", "epilepsy-COVID", "COVID-encephalopathy", "SARS-CoV-2-encephalitis", "SARS-CoV-2-rhabdomyolysis", "COVID-demyelinating disease", "neurological manifestations", "psychosocial manifestations", "treatment recommendations", "COVID-19 and therapeutic changes", "psychiatry", "marginalised", "telemedicine", "mental health", "quarantine", "infodemic" and "social media". A few newspaper reports related to COVID-19 and psychosocial impacts have also been added as per context.
resultsNeurological and neuropsychiatric manifestations of COVID-19 are abundant. Clinical features of both central and peripheral nervous system involvement are evident. These have been categorically analyzed briefly with literature support. Most of the psychological effects are secondary to pandemic-associated regulatory, socioeconomic and psychosocial changes.
conclusionNeurological and neuropsychiatric manifestations of this disease are only beginning to unravel. This demands a wide index of suspicion for prompt diagnosis of SARS-CoV-2 to prevent further complications and mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.