Evidence map›Paper›PMID 32753017›Full record

ArticleCurrent HIV research2020

Clinical Outcomes of Post-exposure Prophylaxis following Occupational Exposure to Human Immunodeficiency Virus at Dental Departments of Hiroshima University Hospital.

T Shintani, T Iwata, M Okada, M Nakaoka, N Yamasaki, T Fujii, H Shiba

Open access · greenAbstract read
In one paragraph

Article in Current HIV research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV - CDC Recommendations, United States, 2025.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2025
    Guideline
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

T ShintaniCenter of Oral Clinical Examination, Hiroshima University Hospital, Japan
T IwataDepartment of Periodontal Medicine, Graduate School of Biomedical & Sciences, Hiroshima University, Japan
M OkadaDivision of Dental Hygiene, Department of Clinical Practice and Support, Hiroshima University Hospital, Japan.
M NakaokaDivision of Dental Hygiene, Department of Clinical Practice and Support, Hiroshima University Hospital, Japan.
N YamasakiDivision of Blood Transfusion, Hiroshima University Hospital, Japan
T FujiiDivision of Blood Transfusion, Hiroshima University Hospital, Japan
H ShibaCenter of Oral Clinical Examination, Hiroshima University Hospital, Japan
Hiroshima University Hospital · JPHiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDental professionals have so many opportunities to use injection needles and sharp instruments during dental treatment that they face an increased risk of needlestick injuries. This retrospective study reports the utilization and clinical outcomes of occupational post-exposure prophylaxis (PEP) with anti-retroviral agents after being potentially exposed to HIV at the dental departments of Hiroshima University Hospital.

objectiveThis study reports the utilization and clinical outcomes of occupational post-exposure prophylaxis (PEP) with antiretroviral agents after being potentially exposed to HIV at dental departments of Hiroshima University Hospital.

methodsData on the clinical status of HIV-infected source patients and information on HIV-exposed dental professionals from 2007 to 2018 were collected.

resultsFive dentists with an average experience of 5.6 years (1-15 years) were exposed. The averaged CD4-positive cell number and HIV-RNA load were 1176 (768-1898) /μl and less than 20 copies/ml, respectively, in all the patients. Two of the five HIV exposed dentists received PEP. Three months after the exposures, all of their results were negative in HIV antibody/antigen tests.

conclusion; These data might support the concept of "undetectable equals untransmittable", although HIV exposure in this study was not through sexual transmission.

Indexed as

AdultAnti-HIV AgentsAnti-Retroviral AgentsDental ClinicsDentistsFemaleHIV InfectionsHospitals, UniversityHumansJapanMaleMiddle AgedNeedlestick InjuriesOccupational ExposurePost-Exposure ProphylaxisRetrospective StudiesAnti-HIV AgentsAnti-Retroviral Agentsdental treatmentHIVneedlestick injuryoccupational exposurespost-exposure prophylaxisU=U

Identifiers

PMID32753017
PMCPMC8388063
OpenAlexW3047400961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.