Evidence map›Paper›PMID 32752177›Full record

ArticleMarine drugs2020

New Cytotoxic Cerebrosides from the Red Sea Cucumber

Reda F A Abdelhameed, Enas E Eltamany, Dina M Hal, Amany K Ibrahim, Asmaa M AboulMagd, Tarfah Al-Warhi, Khayrya A Youssif, Adel M Abd El-Kader, Hashim A Hassanean, Shaimaa Fayez and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Reda F A AbdelhameedDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-1743-0942
Enas E EltamanyDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0003-1607-4285
Dina M HalDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Amany K IbrahimDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Asmaa M AboulMagdDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Nahda University, Beni Suef 62513, Egypt.ORCID 0000-0003-4243-9401
Tarfah Al-WarhiDepartment of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 13414, Saudi Arabia.
Khayrya A YoussifDepartment of Pharmacognosy, Faculty of Pharmacy, Modern University for Technology and Information, Cairo 11566, Egypt.
Adel M Abd El-KaderDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia 61111, Egypt.
Hashim A HassaneanDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Shaimaa FayezInstitute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.ORCID 0000-0001-6508-0900
Gerhard BringmannInstitute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.ORCID 0000-0002-3583-5935
Safwat A AhmedDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia 61111, Egypt.ORCID 0000-0002-1014-6922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactivity-guided fractionation of a methanolic extract of the Red Sea cucumber

Indexed as

AnimalsAntineoplastic AgentsBreast NeoplasmsCerebrosidesDNA-Binding ProteinsDose-Response Relationship, DrugFemaleHCT116 CellsHeLa CellsHep G2 CellsHistone ChaperonesHolothuriaHumansInhibitory Concentration 50MaleMCF-7 CellsAntineoplastic AgentsCerebrosidesDNA-Binding ProteinsHistone ChaperonesProtein Phosphatase 2SET protein, humancerebrosidescytotoxicityHolothuria spiniferaLC-HRESIMSmolecular docking

Identifiers

PMID32752177
PMCPMC7460232

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.