Evidence map›Paper›PMID 32752153›Full record

ReviewCancers2020

Recent Advances in Desmoid Tumor Therapy.

Andrea Napolitano, Alessandro Mazzocca, Mariella Spalato Ceruso, Alessandro Minelli, Francesca Baldo, Giuseppe Badalamenti, Marianna Silletta, Daniele Santini, Giuseppe Tonini, Lorena Incorvaia and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

  1. Phase III Trial of Pegylated Liposomal Doxorubicin for Patients with Advanced and Refractory Desmoid Tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Long-term outcome and prognostic factors after chest wall resection and reconstruction.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  7. A giant sporadic intra-abdominal desmoid tumor resection: a rare case report.International journal of surgery case reports · 2025
    Article
  8. Article
  9. Evolution of Initial Treatment for Desmoid Tumors.Annals of surgical oncology · 2024
    Article
  10. New strategies in soft tissue sarcoma treatment.Journal of hematology & oncology · 2024
    Review
  11. Aggressive fibromatosis of the sigmoid colon: A case report.World journal of gastrointestinal oncology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Giant abdominal desmoid-type fibromatosis.Autopsy & case reports · 2024
    Article
  16. Review
  17. Article
  18. Desmoid Tumors: A Comprehensive Review.Advances in therapy · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Andrea NapolitanoDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-7509-1555
Alessandro MazzoccaDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Mariella Spalato CerusoDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Alessandro MinelliDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Francesca BaldoDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Giuseppe BadalamentiDepartment of Medical Oncology, Policlinico "Paolo Giaccone", 90127 Palermo, Italy.
Marianna SillettaDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Daniele SantiniDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Giuseppe ToniniDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Lorena IncorvaiaDepartment of Medical Oncology, Policlinico "Paolo Giaccone", 90127 Palermo, Italy.ORCID 0000-0002-1199-7286
Bruno VincenziDepartment of Medical Oncology, Università Campus Bio-Medico, 00128 Rome, Italy.
Università Campus Bio-Medico · ITAzienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The desmoid tumor is a locally aggressive proliferative disease within the family of soft-tissue sarcomas. Despite its relatively good prognosis, the clinical management of desmoid tumors requires constant multidisciplinary evaluation due to its highly variable clinical behavior. Recently, active surveillance has being regarded as the appropriate strategy at diagnosis, as indolent persistence or spontaneous regressions are not uncommon. Here, we review the most recent advances in desmoid tumor therapy, including low-dose chemotherapy and treatment with tyrosine kinase inhibitors. We also explore the recent improvements in our knowledge of the molecular biology of this disease, which are leading to clinical trials with targeted agents.

Indexed as

active surveillanceaggressive fibromatosischemotherapydesmoid tumortyrosine kinase inhibitors

Identifiers

PMID32752153
PMCPMC7463981
OpenAlexW3046362099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.