ArticleFoods (Basel, Switzerland)2020
LC-MS/MS Analysis of Choline Compounds in Japanese-Cultivated Vegetables and Fruits.
Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Optimisation of acid hydrolysis conditions of choline esters and mass spectrometric determination of total choline in various foods.Scientific reports · 2024Article
- Evaluation of the Antihypertensive Activity of Eggplant Acetylcholine and γ-Aminobutyric Acid in Spontaneously Hypertensive Rats.Molecules (Basel, Switzerland) · 2023Article
- Correction: Wang et al. LC-MS/MS Analysis of Choline Compounds in Japanese-Cultivated Vegetables and Fruits.Foods (Basel, Switzerland) · 2022Article
- Antihypertensive Mechanism of Orally Administered Acetylcholine in Spontaneously Hypertensive Rats.Nutrients · 2022Article
- Differential Antihypertensive Effects of Oral Doses of Acetylcholine between Spontaneously Hypertensive Rats and Normotensive Rats.Foods (Basel, Switzerland) · 2021Article
- Investigation of the Distribution and Content of Acetylcholine, a Novel Functional Compound in Eggplant.Foods (Basel, Switzerland) · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
Choline is an essential nutrient and choline esters are potential functional food ingredients. We aimed to analyze the choline compound content in 19 cultivated fruits and vegetables and identify those with high acetylcholine content. We utilized liquid chromatography with tandem mass spectrometry to quantify choline compounds according to the standard addition method. Choline compounds were extracted from lyophilized fruit/vegetable powders and passed through a weakly acidic cation exchange column, resulting in a concentrated solution of choline compounds. The compounds were separated on a pentafluorophenyl column and then analyzed using positive mode electrospray ionization. Results showed that acetylcholine and choline were the primary choline compounds in all agricultural products; propionylcholine and butyrylcholine were minor compounds in 17 and 12 agricultural products, respectively. The acetylcholine concentration was 2900-fold higher in eggplants (6.12 mg/100 g fresh weight [FW]) than in other agricultural products (average: 2.11 × 10
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Registered trials
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