Evidence map›Paper›PMID 32752065›Full record

ArticleMaterials (Basel, Switzerland)2020

Xeno-Free In Vitro Cultivation and Osteogenic Differentiation of hAD-MSCs on Resorbable 3D Printed RESOMER

Marline Kirsch, Annabelle-Christin Herder, Cécile Boudot, Andreas Karau, Jessica Rach, Wiebke Handke, Axel Seltsam, Thomas Scheper, Antonina Lavrentieva

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Marline KirschInstitute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167 Hannover, Germany.ORCID 0000-0003-1102-9354
Annabelle-Christin HerderInstitute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167 Hannover, Germany.
Cécile BoudotEvonik Nutrition & Care GmbH, Business Line Health Care, Kirschenallee, 64293 Darmstadt, Germany.
Andreas KarauEvonik Nutrition & Care GmbH, Business Line Health Care, Kirschenallee, 64293 Darmstadt, Germany.
Jessica RachGerman Red Cross Blood Service NSTOB, Institute Springe, Eldagsener Straße 38, 31830 Springe, Germany.
Wiebke HandkeBavarian Red Cross Blood Service, Institute Nuremberg, Heimerichstrasse 57, 90419 Nuremberg, Germany.
Axel SeltsamBavarian Red Cross Blood Service, Institute Nuremberg, Heimerichstrasse 57, 90419 Nuremberg, Germany.
Thomas ScheperInstitute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167 Hannover, Germany.
Antonina LavrentievaInstitute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167 Hannover, Germany.
Leibniz University Hannover · DEGerman Red Cross · DEEvonik (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of alloplastic resorbable materials can revolutionize the field of implantation technology in regenerative medicine. Additional opportunities to colonize the three-dimensionally (3D) printed constructs with the patient's own cells prior to implantation can improve the regeneration process but requires optimization of cultivation protocols. Human platelet lysate (hPL) has already proven to be a suitable replacement for fetal calf serum (FCS) in 2D and 3D cell cultures. In this study, we investigated the in vitro biocompatibility of the printed RESOMER

Indexed as

3D printingadipose tissue-derived mesenchymal stem cells (hAD-MSCs)fetal calve serumhuman platelet lysatehuman serumin vitro biocompatibilityin vitro degradationosteogenic differentiationRESOMER®resorbable polymers

Identifiers

PMID32752065
PMCPMC7436127
OpenAlexW3046727008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.