Evidence map›Paper›PMID 32751915›Full record

ArticleJournal of fungi (Basel, Switzerland)2020

Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in

Hannah L Norris, Rohitashw Kumar, Chih Yean Ong, Ding Xu, Mira Edgerton

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploring the Healing Powers of Histatins: From Oral Health to Therapeutics.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Antifungal Peptides.Journal of fungi (Basel, Switzerland) · 2021
    Article
  15. Membrane-Interacting Antifungal Peptides.Frontiers in cell and developmental biology · 2021
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hannah L NorrisDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Foster Hall Buffalo, NY 14214, USA.
Rohitashw KumarDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Foster Hall Buffalo, NY 14214, USA.ORCID 0000-0001-8695-3555
Chih Yean OngDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Foster Hall Buffalo, NY 14214, USA.
Ding XuDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Foster Hall Buffalo, NY 14214, USA.
Mira EdgertonDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Foster Hall Buffalo, NY 14214, USA.
University at Buffalo, State University of New York · US

Funding

Supplements to Support Candida DNA Microarray FacilitiesR01DE010641 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EDGERTON, MIRA · 2000 to 2019
$6.7M
Heparan Sulfate–Osteoprotegerin Interactions in Bone RemodelingR01AR070179 · NIAMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI XU, DING · 2017 to 2021
$1.7M
A novel metal-starvation candidacidal mechanism for Histatin 5F31DE028458 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI NORRIS, HANN L · 2018 to 2021
$90k
NIAMS NIH HHS R01AR070179NIDCR NIH HHS F31DE028458NIDCR NIH HHS R01DE010641
6 · The paper itself

Abstract

Histatin 5 (Hst 5) is an antimicrobial peptide produced in human saliva with antifungal activity for opportunistic pathogen

Indexed as

Candida albicansCandida glabrataHistatin 5membrane disruptionP113zinc

Identifiers

PMID32751915
PMCPMC7559477
OpenAlexW3046338717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.