ReviewJournal of clinical medicine2020
Intraventricular Hemorrhage in Very Preterm Infants: A Comprehensive Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Comprehensive evaluation of risk factors for intraventricular hemorrhage in preterm neonates: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- Pooled prevalence and predictors of intraventricular hemorrhage (IVH) in preterm neonates (28-34 weeks) in Africa: a systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- [Influence of umbilical cord milking versus delayed cord clamping on the early prognosis of preterm infants with a gestational age of <34 weeks: a Meta analysis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Pooled it
- Midline Head Position for Preterm Infants in the First 72 h: A Pilot Randomised Control Trial.Journal of paediatrics and child health · 2025Trial
- Intraventricular hemorrhage profile in very low birth weight preterm infants (< 1000 g and ≥ 1000 g) at a tertiary center in São Paulo State over a decade.Clinics (Sao Paulo, Brazil) · 2026Article
- Association of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors with Intraventricular Haemorrhage in Preterm Infants.International journal of molecular sciences · 2026Article
- Maternal and neonatal outcomes and histological chorioamnionitis in preterm premature rupture of membranes complicated by group B streptococcus colonization: a retrospective analysis.BMC pregnancy and childbirth · 2026Article
- Transforming neonatal care through informatics: A review of artificial intelligence, data, and implementation considerations.Seminars in perinatology · 2025Review
- Poor Correlation Between Inflammatory and Brain Injury Biomarkers After Neonatal Intraventricular Hemorrhage: A Pilot Study.World neurosurgery · 2025Article
- Paediatric cranial ultrasound: assessment of the preterm brain.Insights into imaging · 2025Article
- Prevalence of intraventricular hemorrhage and associated factors to in premature babies in selected teaching hospitals in Rwanda.BMC pediatrics · 2025Article
- Cerebellar haemorrhage and atrophy in infants born extremely preterm with intraventricular haemorrhage.Developmental medicine and child neurology · 2025Article
- Activin-A urine levels correlate with radiological patterns in preterm infants complicated by intraventricular hemorrhage.Italian journal of pediatrics · 2025Observational
- Article
- Identification of CSPG4 as a Biomarker and Therapeutic Target for Infantile Post-Hemorrhagic Hydrocephalus via Multi-Omics Analysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Development and validation of a nomogram for predicting early-onset severe intraventricular hemorrhage in extremely preterm infants.Frontiers in pediatrics · 2025Article
- Navigating challenges in hydrocephalus following intraventricular hemorrhage: a comprehensive review of current evidence.Frontiers in neurology · 2025Review
- Prediction models for intraventricular hemorrhage in very preterm infants: a systematic review.Frontiers in pediatrics · 2025Review
- International Variation and Trends of Intraventricular Hemorrhage in Very Preterm Infants.Neonatology · 2025Article
- Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study.BMC pediatrics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Germinal matrix-intraventricular-intraparenchymal hemorrhage (GMH-IVH-IPH) is a major complication of very preterm births before 32 weeks of gestation (WG). Despite progress in clinical management, its incidence remains high before 27 WG. In addition, severe complications may occur such as post-hemorrhagic hydrocephalus and/or periventricular intraparenchymal hemorrhage. IVH is strongly associated with subsequent neurodevelopmental disabilities. For this review, an automated literature search and a clustering approach were applied to allow efficient filtering as well as topic clusters identification. We used a programmatic literature search for research articles related to intraventricular hemorrhage in preterms that were published between January 1990 and February 2020. Two queries ((Intraventricular hemorrhage) AND (preterm)) were used in PubMed. This search resulted in 1093 articles. The data manual curation left 368 documents that formed 12 clusters. The presentation and discussion of the clusters provide a comprehensive overview of existing data on the pathogenesis, complications, neuroprotection and biomarkers of GMH-IVH-IPH in very preterm infants. Clinicians should consider that the GMH-IVH-IPH pathogenesis is mainly due to developmental immaturity of the germinal matrix and cerebral autoregulation impairment. New multiomics investigations of intraventricular hemorrhage could foster the development of predictive biomarkers for the benefit of very preterm newborns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.