Evidence map›Paper›PMID 32751788›Full record

Trial reportNutrients2020

Casein Protein Processing Strongly Modulates Post-Prandial Plasma Amino Acid Responses In Vivo in Humans.

Jorn Trommelen, Michelle E G Weijzen, Janneau van Kranenburg, Renate A Ganzevles, Milou Beelen, Lex B Verdijk, Luc J C van Loon

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Ingestion of 'whole cell' or 'split cell'Frontiers in nutrition · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jorn TrommelenNUTRIM School of Nutrition and Translation Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
Michelle E G WeijzenNUTRIM School of Nutrition and Translation Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.ORCID 0000-0001-6859-7606
Janneau van KranenburgNUTRIM School of Nutrition and Translation Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
Renate A GanzevlesFrieslandCampina, Stationsplein 4, 3818 LE Amstersfoort, The Netherlands.
Milou BeelenNUTRIM School of Nutrition and Translation Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
Lex B VerdijkNUTRIM School of Nutrition and Translation Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
Luc J C van LoonNUTRIM School of Nutrition and Translation Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-6768-9231
Maastricht University Medical Centre · NLFrieslandCampina (Netherlands) · NL

Funding

TI Food and Nutrition not available
6 · The paper itself

Abstract

Micellar casein is characterized as a slowly digestible protein source, and its structure can be modulated by various food processing techniques to modify its functional properties. However, little is known about the impact of such modifications on casein protein digestion and amino acid absorption kinetics and the subsequent post-prandial plasma amino acid responses. In the present study, we determined post-prandial aminoacidemia following ingestion of isonitrogenous amounts of casein protein (40 g) provided as micellar casein (Mi-CAS), calcium caseinate (Ca-CAS), or cross-linked sodium caseinate (XL-CAS). Fifteen healthy, young men (age: 26 ± 4 years, BMI: 23 ± 1 kg·m

Indexed as

AdultAmino AcidsArea Under CurveCaseinsChromatography, High Pressure LiquidCross-Over StudiesDietary ProteinsDigestionEatingGastrointestinal AbsorptionHealthy VolunteersHumansMalePostprandial PeriodYoung AdultAmino Acidscalcium caseinateCaseinsDietary Proteinscoagulationdairydigestibilityleucinemetabolismmilkprotein qualityprotein synthesissolubilitysupplementation

Identifiers

PMID32751788
PMCPMC7468913
OpenAlexW3045771502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.