Evidence map›Paper›PMID 32751713›Full record

ArticleInternational journal of molecular sciences2020

Clinical Significance of Expression Changes and Promoter Methylation of PLA2R1 in Tissues of Breast Cancer Patients.

Noha Mitwally, Einas Yousef, Ahmad Abd Al Aziz, Mohamed Taha

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Epigenetics · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Noha MitwallyDepartment of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID 0000-0002-0866-0981
Einas YousefBasic Medical Sciences Department, College of Medicine, Dar Al Uloom University, Riyadh 7222, Saudi Arabia.ORCID 0000-0002-8935-0183
Ahmad Abd Al AzizSurgery Department, Faculty of Medicine, Kasr Al Ainy Hospital, Cairo University, Cairo 11562, Egypt.
Mohamed TahaDepartment of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID 0000-0002-9806-826X
Cairo University · EGDar Al Uloom University · SA

Funding

Deanship of Postgraduate and Scientific Research at Dar Al Uloom University ---------
6 · The paper itself

Abstract

Phospholipase A2 receptor 1 (PLA2R1) expression and its role in the initiation and progression of breast cancer are an unresolved issue. PLA2R1 was found to endorse several tumor suppressive responses, including cellular senescence and apoptosis. Previous in vitro studies demonstrated that DNA hypermethylation was highly associated with the epigenetic silencing of

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsCell Line, TumorDNA MethylationEpigenesis, GeneticFemaleGene Expression Regulation, NeoplasticHumansMiddle AgedPromoter Regions, GeneticReceptors, Phospholipase A2Triple Negative Breast NeoplasmsPLA2R1 protein, humanReceptors, Phospholipase A2bioinformatics analysisbreast cancerPLA2R1promoter methylationTNBC

Identifiers

PMID32751713
PMCPMC7432085
OpenAlexW3045499367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.