Evidence map›Paper›PMID 32751655›Full record

ArticleSensors (Basel, Switzerland)2020

Critical Factors for In Vivo Measurements of Human Skin by Terahertz Attenuated Total Reflection Spectroscopy.

Lixia Wang, Sayon Guilavogui, Henghui Yin, Yiping Wu, Xiaofei Zang, Jingya Xie, Li Ding, Lin Chen

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Biomedical application of terahertz imaging technology: a narrative review.Quantitative imaging in medicine and surgery · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lixia WangShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Sayon GuilavoguiShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Henghui YinShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Yiping WuShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Xiaofei ZangShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Jingya XieShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Li DingShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.
Lin ChenShanghai Key Lab of Modern Optical System, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Terahertz Technology Innovation Research Institute, University of Shanghai for Science and Technology, Shanghai 200093, China.ORCID 0000-0002-6848-5257

Funding

the National Key R&D Program of China 2018YFF01013003the National Natural Science Foundation of China Nos. 61671302the Shuguang Program Supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission No. 18SG44
6 · The paper itself

Abstract

Attenuated total reflection (ATR) geometry is a suitable choice for in vivo measurements of human skin due to the deep penetration of the field into the sample and since it makes it easy to measure the reference spectrum. On the other hand, there are several critical factors that may affect the terahertz (THz) response in these kinds of experiments. Here, we analyse in detail the influence of the following factors: the contact positions between the thumb and the prism, the contact pressure, the contact duration, and the materials of the prism. Furthermore, we use the THz-ATR technology to evaluate different types of handcream and also establish the theoretical model to investigate the reflectivity after interacting with the skin. The results agree well with experimental ones. Our analysis makes it clear the importance of controlling the above factors during measurements to enable reliable THz response and results which, in turn, may be used to monitor water motion in human skin and to predict possible diseases.

Indexed as

SkinTerahertz SpectroscopyHumansModels, TheoreticalOptical ImagingWaterWaterattenuated total reflectionhuman skinin vivoterahertz time-domain spectroscopy

Identifiers

PMID32751655
PMCPMC7436154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.