ReviewBioengineering (Basel, Switzerland)2020
Emerging Contact-Killing Antibacterial Strategies for Developing Anti-Biofilm Dental Polymeric Restorative Materials.
Review in Bioengineering (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Antimicrobial additives in resin-based endodontic sealers: a scoping review of antimicrobial efficacy, physicochemical properties, and cytotoxicity.Frontiers in dental medicine · 2026Pooled it
- Applications of Nanomaterials in Restorative Dentistry and Endodontics: A Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Hyperbranched Polymer Dendrimers Embedded in Electrospun Nanofibers for Safe and Sustainable Antibacterial Filtration Materials.Polymers · 2026Article
- Comparative Evaluation of Mechanical Properties, Color Stability, and Surface Roughness of Gingiva-Shaded Composites.International journal of dentistry · 2026Article
- A novel dual-targeting strategy to suppress cariogenic bacteria and biofilms with engineered ARG/FBG bioactive composites.Regenerative biomaterials · 2026Article
- Innovative Smart Materials in Restorative Dentistry.Journal of functional biomaterials · 2025Review
- Development of Substrate-Independent Antifouling and Bactericidal Surfaces Using Visible Light Cross-Linked Hydrogel Coatings for Biomedical Applications.Advanced healthcare materials · 2025Article
- A Modified Bioceramic Sealer with Dual Antibacterial Mechanisms.Bioengineering (Basel, Switzerland) · 2025Article
- Cariogenic Microbiota and Emerging Antibacterial Materials to Combat Dental Caries: A Literature Review.Pathogens (Basel, Switzerland) · 2025Review
- The impact of dimethylaminohexadecyl methacrylates on the physical and antibacterial properties of endodontic sealers.Frontiers in oral health · 2025Article
- Current approaches to produce durable biomaterials: Trends in polymeric materials for restorative dentistry applications.Dental materials : official publication of the Academy of Dental Materials · 2024Review
- Article
- The activity of hydrolytic enzymes and antibiotics against biofilms of bacteria isolated from industrial-scale cooling towers.Microbial cell factories · 2024Article
- Recent Advances in Antibacterial Coatings to Combat Orthopedic Implant-Associated Infections.Molecules (Basel, Switzerland) · 2024Review
- Testing mechanical properties and degree of conversion of resin-based composite material containing contact killing antibacterial agent in comparison with fluoride composite resin.The Saudi dental journal · 2024Article
- Characteristics and Key Features of Antimicrobial Materials and Associated Mechanisms for Diverse Applications.Molecules (Basel, Switzerland) · 2023Review
- Norlobaridone Inhibits Quorum Sensing-Dependent Biofilm Formation and Some Virulence Factors inBiomolecules · 2023Article
- The germicidal effect, biosafety and mechanical properties of antibacterial resin composite in cavity filling.Heliyon · 2023Review
- Smart dental materials for antimicrobial applications.Bioactive materials · 2023Article
- Inorganic Compounds as Remineralizing Fillers in Dental Restorative Materials: Narrative Review.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Polymeric materials are the first choice for restoring tooth cavities, bonding tooth-colored fillings, sealing root canal systems, and many other dental restorative applications. However, polymeric materials are highly susceptible to bacterial attachment and colonization, leading to dental diseases. Many approaches have been investigated to minimize the formation of biofilms over polymeric restorative materials and at the tooth/material interfaces. Among them, contact-killing compounds have shown promising results to inhibit dental biofilms. Contact-killing compounds can be immobilized within the polymer structure, delivering a long-lasting effect with no leaching or release, thus providing advantages compared to release-based materials. This review discusses cutting-edge research on the development of contact-killing compounds in dental restorative materials to target oral pathogens. Contact-killing compounds in resin composite restorations, dental adhesives, root canal sealers, denture-based materials, and crown cements have all demonstrated promising antibacterial properties. Contact-killing restorative materials have been found to effectively inhibit the growth and activities of several oral pathogens related to dental caries, periodontal diseases, endodontic, and fungal infections. Further laboratory optimization and clinical trials using translational models are needed to confirm the clinical applicability of this new generation of contact-killing dental restorative materials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.