Evidence map›Paper›PMID 32751549›Full record

ArticleCells2020

Ligation of MHC Class II Induces PKC-Dependent Clathrin-Mediated Endocytosis of MHC Class II.

Kento Masaki, Yuhji Hiraki, Hiroka Onishi, Yuka Satoh, Paul A Roche, Satoshi Tanaka, Kazuyuki Furuta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kento MasakiDepartment of Immunobiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Tsushima naka 1-1-1, Kita-ku, Okayama 700-8530, Japan.
Yuhji HirakiDepartment of Immunobiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Tsushima naka 1-1-1, Kita-ku, Okayama 700-8530, Japan.
Hiroka OnishiDepartment of Immunobiology, Faculty of Pharmacy and Pharmaceutical Sciences, Okayama University, Tsushima naka 1-1-1, Kita-ku, Okayama 700-8530, Japan.
Yuka SatohDepartment of Immunobiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Tsushima naka 1-1-1, Kita-ku, Okayama 700-8530, Japan.
Paul A RocheExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Satoshi TanakaDepartment of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Misasagi Nakauchi-cho 5, Yamashina-ku, Kyoto 607-8414, Japan.ORCID 0000-0002-3468-7694
Kazuyuki FurutaDepartment of Immunobiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Tsushima naka 1-1-1, Kita-ku, Okayama 700-8530, Japan.
Okayama University · JPKyoto Pharmaceutical University · JPNational Institutes of Health · US

Funding

Regulation of MHC Class II Trafficking in Antigen Presenting CellsZIABC009404 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROCHE, PAUL · 2009 to 2025
$17.9M
Mechanisms of MHC Class II Association with Plasma Membrane MicrodomainsZIABC011033 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROCHE, PAUL · 2009 to 2020
$3.4M
6 · The paper itself

Abstract

In addition to antigen presentation to CD4

Indexed as

AnimalsAntigen PresentationBone Marrow CellsCalciumCells, CulturedClathrinCross-Linking ReagentsDendritic CellsEndocytosisEstrenesHistocompatibility Antigens Class IIMaleMicePhorbol EstersProtein Kinase CPyrrolidinones1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione3,3',4,5'-tetrahydroxystilbeneCalciumClathrinCross-Linking ReagentsEstrenesHistocompatibility Antigens Class IIPhorbol EstersProtein Kinase CPyrrolidinonesStaurosporineStilbenesSyk KinaseSyk protein, mouseType C Phospholipasescrosslinkdendritic cellsendocytosisMHC-IIPKC

Identifiers

PMID32751549
PMCPMC7465434
OpenAlexW3045990564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.