ReviewInternational journal of molecular sciences2020
Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04916743 (The Effect of Intradialytic Exercise on Calcium, Phosphorus and Parathyroid Hormone), which is not on this map. Cited by 60 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Intradialytic Exercise on Calcium, Phosphorus and Parathyroid Hormone: A Randomized Controlled Trial
Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Effect of Exercise on Parathyroid Hormone Levels in Dialysis Patients: A Systematic Review and Meta-Analysis.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Pooled it
- Effect of Calcium Citrate Versus Calcium Carbonate on Parathyroid Hormone Levels in Patients Undergoing Bariatric Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Obesity surgery · 2026Pooled it
- Association of parathyroid hormone with risk of hypertension and type 2 diabetes: a dose-response meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Trial
- Effect of walking and bone joint exercise on enhancing bone remodeling in menopausal women: A randomized controlled trial.Narra J · 2024Trial
- High-intensity interval training improves bone remodeling, lipid profile, and physical function in multiple sclerosis patients.Scientific reports · 2024Trial
- The effect of intradialytic exercise on calcium, phosphorus and parathyroid hormone: a randomized controlled trial.BMC nephrology · 2023Trial
- Calcium Homeostasis and Parturient Paresis in Ruminants: Mechanistic Insights and Clinical Management.Animals : an open access journal from MDPI · 2026Review
- Exercise-Induced Coronary Remodeling and the Atherosclerotic Paradox in Endurance Athletes: Toward a Unified Mechanobiological Framework.Journal of functional morphology and kinesiology · 2026Review
- The effect of preoperative rehabilitation exercises on postoperative bone mineral density, tendon-bone healing, and physical function after anterior cruciate ligament reconstruction: a multi-center randomized controlled clinical trial.BMC sports science, medicine & rehabilitation · 2026Article
- Prevalence and determinants of secondary hyperparathyroidism: IMOS-2021.Scientific reports · 2026Article
- Stem Cells and their Key Derivatives in Degenerative Musculoskeletal Diseases.Stem cell reviews and reports · 2026Review
- The impact of hyperparathyroidism on skeletal muscle pathophysiology and physical function.Endocrine connections · 2026Review
- Coronary atherosclerosis in athletes: emerging concepts and preventive strategies.European heart journal · 2025Review
- Feasibility and safety of impact-loading exercise in patients with multiple myeloma-a pilot study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Dissecting the bidirectional associations between the progression of gastrointestinal and endocrine diseases.Frontiers in endocrinology · 2025Article
- Association of serum parathyroid hormone within normal range with the prevalence and prognosis among adults with diabetes and prediabetes: insight from NHANES 2003-2006 data.Therapeutic advances in endocrinology and metabolism · 2025Article
- A novel LC-MS/MS analysis of vitamin D metabolites in mice serum and hair: impact of diet and light exposure.Frontiers in endocrinology · 2025Article
- Involvement of Phosphate and the Consequences of Its High Consumption in Energy Metabolism and Muscle Functions.Journal of nutrition and metabolism · 2025Review
- A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk.Biology of sport · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Exercise perturbs homeostasis, alters the levels of circulating mediators and hormones, and increases the demand by skeletal muscles and other vital organs for energy substrates. Exercise also affects bone and mineral metabolism, particularly calcium and phosphate, both of which are essential for muscle contraction, neuromuscular signaling, biosynthesis of adenosine triphosphate (ATP), and other energy substrates. Parathyroid hormone (PTH) is involved in the regulation of calcium and phosphate homeostasis. Understanding the effects of exercise on PTH secretion is fundamental for appreciating how the body adapts to exercise. Altered PTH metabolism underlies hyperparathyroidism and hypoparathyroidism, the complications of which affect the organs involved in calcium and phosphorous metabolism (bone and kidney) and other body systems as well. Exercise affects PTH expression and secretion by altering the circulating levels of calcium and phosphate. In turn, PTH responds directly to exercise and exercise-induced myokines. Here, we review the main concepts of the regulation of PTH expression and secretion under physiological conditions, in acute and chronic exercise, and in relation to PTH-related disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.