Evidence map›Paper›PMID 32751290›Full record

ArticleNutrients2020

The Association between Seafood Intake and Fecundability: Analysis from Two Prospective Studies.

Lauren A Wise, Sydney K Willis, Ellen M Mikkelsen, Amelia K Wesselink, Henrik Toft Sørensen, Kenneth J Rothman, Katherine L Tucker, Ellen Trolle, Marco Vinceti, Elizabeth E Hatch

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Omega-3 fatty acid supplementation and fecundability.Human reproduction (Oxford, England) · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Lauren A WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.ORCID 0000-0003-2138-3752
Sydney K WillisDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
Ellen M MikkelsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Nordre Ringgade 1, Aarhus C, 8000 Aarhus, Denmark.
Amelia K WesselinkDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.ORCID 0000-0002-3929-4451
Henrik Toft SørensenDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
Kenneth J RothmanDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
Katherine L TuckerDepartment of Biomedical and Nutritional Sciences, College of Health Sciences, University of Massachusetts Lowell, Pawtucket St, Lowell, MA 01854, USA.ORCID 0000-0001-7640-662X
Ellen TrolleNational Food Institute, Technical University of Denmark, 2800 Kgs Lyngby, Denmark.
Marco VincetiDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.ORCID 0000-0002-0551-2473
Elizabeth E HatchDepartment of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
Boston University · USAarhus University Hospital · DKTechnical University of Denmark · DKUniversity of Massachusetts Lowell · US

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
NICHD NIH HHS R01 HD086742
6 · The paper itself

Abstract

backgroundSeafood is an important source of omega-3 fatty acids, which have been associated with improved oocyte quality and embryo morphology in some studies. However, seafood is also a source of persistent organic pollutants and heavy metals, which may adversely affect fecundity. Previous studies of seafood intake and fecundity have generated inconsistent results.

methodsIn two prospective cohort studies of 7836 female pregnancy planners from Denmark (Snart Foraeldre,

resultsIntake of total seafood or marine-sourced long-chain omega-3 fatty acids was not appreciably associated with fecundability in either cohort (≥200 vs. <50 g/week total seafood: FR = 0.94, 95% CI: 0.79-1.10 in Snart Foraeldre; FR = 1.00, 95% CI: 0.90-1.13 in PRESTO; marine fatty acids: ≥90th vs. <25th percentile: FR = 1.00, 95% CI: 0.85-1.18 in Snart Foraeldre; FR = 0.97, 95% CI: 0.86-1.09 in PRESTO). In PRESTO, where we collected additional data on seafood preparation, we observed an inverse association between fecundability and fried shellfish (≥10 g/week vs. none: FR = 0.77, 95% CI: 0.61-0.98), but not unfried shellfish (≥20 g/week vs. none: FR = 0.98, 95% CI: 0.89-1.07); in Snart Foraeldre, there was no association with total shellfish intake.

conclusionsWe found little association between seafood intake and fecundability overall, but greater intake of fried shellfish was associated with reduced fecundability among North American participants.

Indexed as

FertilitySeafoodAdultAnimalsDenmarkDiet SurveysEatingFatty Acids, Omega-3FemaleFishesHumansNorth AmericaPregnancyPregnancy RateProspective StudiesFatty Acids, Omega-3epidemiologyfatty acidsfertilityfishinternetprospective studiesseafood

Identifiers

PMID32751290
PMCPMC7469023
OpenAlexW3046106304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.