ReviewCancers2020
Epithelioid Sarcoma-From Genetics to Clinical Practice.
Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Systematic Review of Published Cases of Primary Epithelioid Sarcoma of the Spine.Medical science monitor : international medical journal of experimental and clinical research · 2023Pooled it
- Epithelioid Sarcoma: A Review and Update.Cancers · 2026Review
- Epithelioid Sarcoma of the Oral Cavity: A Multi-institutional Clinicopathologic and Immunophenotypic Characterization of Five Cases and Comprehensive Literature Review.Head and neck pathology · 2026Review
- Swelling of the Left Upper Limb with Red Papules, Necrosis and Crusting: A Quiz.Acta dermato-venereologica · 2026Article
- Pediatric non-rhabdomyosarcoma bladder tumors (NRBTs): a 20-year retrospective longitudinal cohort study at a tertiary referral center.Translational andrology and urology · 2026Article
- Epithelioid Sarcoma of the Forearm in a 70-Year-Old Woman: A Case Report at a Referral Facility in Tanzania.Clinical case reports · 2026Article
- Case report of epithelioid sarcoma of the vulva.Frontiers in medicine · 2026Article
- Clinical Findings of Rare Ocular Metastasis in a Patient Diagnosed with Epithelioid Sarcoma.Beyoglu eye journal · 2026Article
- Proximal Epithelioid Sarcoma Mimicking Inguinal Inflammation.Diagnostics (Basel, Switzerland) · 2025Article
- A rare cause of diffuse alveolar hemorrhage in a pediatric patient: thigh localization of INI1-deficient epithelioid sarcoma.Orphanet journal of rare diseases · 2025Article
- Proximal-type Epithelioid Sarcoma of the Vulva: A Case Report.Acta medica Philippina · 2025Article
- [Increasingly painful induration of the thumb].Dermatologie (Heidelberg, Germany) · 2024Article
- Primary adrenal epithelioid sarcoma (proximal type): a case report and literature review.The Journal of international medical research · 2024Review
- Lymphadenectomy in the treatment of sarcomas - indications and technique.Oncology reviews · 2024Review
- Delayed diagnosis of pediatric intra-articular epithelioid sarcoma: a case report and literature review.BMC pediatrics · 2023Review
- Epithelioid Sarcoma of the Spine: A Review of Literature and Case Report.Journal of clinical medicine · 2023Article
- Subclassification of epithelioid sarcoma with potential therapeutic impact.The Journal of pathology · 2023Article
- Practical Management of Adult Ultra-Rare Primary Retroperitoneal Soft Tissue Sarcoma: A Focus on Perivascular Epithelioid Tumours and Extraosseous Ewing Sarcoma.Current oncology (Toronto, Ont.) · 2023Review
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Epithelioid sarcoma is a mesenchymal soft tissue sarcoma often arising in the extremities, usually in young adults with a pick of incidence at 35 years of age. Epithelioid sarcoma (ES) is characterized by the loss of SMARCB1/INI1 (integrase interactor 1) or other proteins of the SWI/SNF complex. Two distinct types, proximal and distal, with varying biology and treatment outcomes, are distinguished. ES is known for aggressive behavior, including a high recurrence rate and regional lymph node metastases. An optimal long-term management strategy is still to be defined. The best treatment of localized ES is wide surgical resection. Neo-adjuvant or adjuvant radiotherapy may be recommended, as it reduces the local recurrence rate. Sentinel lymph node biopsy should be considered in ES patients. Patients with metastatic ES have a poor prognosis with an expected median overall survival of about a year. Doxorubicin-based regimens are recommended for advanced ES. Tazemetostat, an EZH2 methyltransferase, has shown promising results in ES patients. Novel therapies, including immunotherapy, are still needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.