Evidence map›Paper›PMID 32751206›Full record

ReviewVaccines2020

Broadly Neutralizing Antibodies for Influenza: Passive Immunotherapy and Intranasal Vaccination.

Mrityunjoy Biswas, Tatsuya Yamazaki, Joe Chiba, Sachiko Akashi-Takamura

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mrityunjoy BiswasDepartment of Microbiology and Immunology, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.ORCID 0000-0002-7798-914X
Tatsuya YamazakiDepartment of Microbiology and Immunology, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.ORCID 0000-0002-2645-6490
Joe ChibaDepartment of Biological Science and Technology, Tokyo University of Science, Tokyo 125-8585, Japan.
Sachiko Akashi-TakamuraDepartment of Microbiology and Immunology, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.ORCID 0000-0003-4890-3172
Aichi Medical University · JPTokyo University of Science · JP

Funding

JSPS 19K07491Takeda Science Foundation 30951902
6 · The paper itself

Abstract

Influenza viruses cause annual epidemics and occasional pandemics. The high diversity of viral envelope proteins permits viruses to escape host immunity. Therefore, the development of a universal vaccine and broadly neutralizing antibodies (bnAbs) is essential for controlling various mutant viruses. Here, we review some potentially valuable bnAbs for influenza; one is a novel passive immunotherapy using a variable domain of heavy chain-only antibody (V

Indexed as

broadly neutralizing mAb (bnAb)camelid variable domain of heavy chain only antibody (VHH)cross protectioninfluenza virusintranasal vaccinationmultidomain antibody (MDAb)passive immunizationpolymeric IgA (pIgA)

Identifiers

PMID32751206
PMCPMC7565570
OpenAlexW3046003587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.