ArticleNutrients2020
Validation and Determination of 25(OH) Vitamin D and 3-Epi25(OH)D3 in Breastmilk and Maternal- and Infant Plasma during Breastfeeding.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- A decade-long assessment reveals persistent vitamin D deficiency and its associated factors in early-pregnant women from northern China (2016-2025).Frontiers in nutrition · 2026Article
- Random forest classification of four unsaturated fatty acids for infection diagnosis and prognosis in female Chinese patients.Annals of medicine and surgery (2012) · 2025Article
- Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong.European journal of nutrition · 2025Article
- Drugs in Human Milk Part 1: Practical and Analytical Considerations in Measuring Drugs and Metabolites in Human Milk.Clinical pharmacokinetics · 2024Review
- Analysis of vitamin DJournal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2024Article
- Quantification and reporting of vitamin D concentrations measured in human milk by LC-MS/MS.Frontiers in nutrition · 2023Review
- Different Vitamin D Supplementation Strategies in the First Years of Life: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Vitamin D in 2020: An Old Pro-Hormone with Potential Effects beyond Mineral Metabolism.Nutrients · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D deficiency in pregnant women and their offspring may result in unfavorable health outcomes for both mother and infant. A 25hydroxyvitamin D (25(OH)D) level of at least 75 nmol/L is recommended by the Endocrine Society. Validated, automated sample preparation and liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods were used to determine the vitamin D metabolites status in mother-infant pairs. Detection of 3-Epi25(OH)D3 prevented overestimation of 25(OH)D3 and misclassification of vitamin D status. Sixty-three percent of maternal 25(OH)D plasma levels were less than the recommended level of 25(OH)D at 3 months. Additionally, breastmilk levels of 25(OH)D decreased from 60.1 nmol/L to 50.0 nmol/L between six weeks and three months (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.