Evidence map›Paper›PMID 32751072›Full record

ReviewInternational journal of molecular sciences2020

Life and Death of Fungal Transporters under the Challenge of Polarity.

Sofia Dimou, George Diallinas

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Nucleoside Transport and Nucleobase Uptake Null Mutants inInternational journal of molecular sciences · 2022
    Article
  4. Article
  5. Article
  6. Membrane Traffic inJournal of fungi (Basel, Switzerland) · 2021
    Review
  7. Article
  8. Microbial Warfare on Three Fronts: Mixed Biofilm ofFrontiers in cellular and infection microbiology · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sofia DimouDepartment of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, 15784 Athens, Greece.
George DiallinasDepartment of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, 15784 Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic plasma membrane (PM) transporters face critical challenges that are not widely present in prokaryotes. The two most important issues are proper subcellular traffic and targeting to the PM, and regulated endocytosis in response to physiological, developmental, or stress signals. Sorting of transporters from their site of synthesis, the endoplasmic reticulum (ER), to the PM has been long thought, but not formally shown, to occur via the conventional Golgi-dependent vesicular secretory pathway. Endocytosis of specific eukaryotic transporters has been studied more systematically and shown to involve ubiquitination, internalization, and sorting to early endosomes, followed by turnover in the multivesicular bodies (MVB)/lysosomes/vacuole system. In specific cases, internalized transporters have been shown to recycle back to the PM. However, the mechanisms of transporter forward trafficking and turnover have been overturned recently through systematic work in the model fungus

Indexed as

Aspergillus nidulansCell MembraneEndocytosisEndoplasmic ReticulumEndosomesFungal ProteinsGene Expression Regulation, FungalGolgi ApparatusLysosomesMembrane Transport ProteinsMultivesicular BodiesProtein TransportSaccharomyces cerevisiaeSecretory PathwayVacuolesFungal ProteinsMembrane Transport ProteinsAspergillus nidulansendocytosisfungiGolgisortingtrafficUapA

Identifiers

PMID32751072
PMCPMC7432044
OpenAlexW3045311518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.