Evidence map›Paper›PMID 32751058›Full record

ArticleCells2020

Comment on: "Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging.

Allen Herbst, Judd M Aiken, Debbie McKenzie, Jonathan Wanagat

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Allen HerbstDepartment of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Judd M AikenDepartment of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Debbie McKenzieDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Jonathan WanagatVeterans Administration Greater Los Angeles Healthcare System, Los Angeles, CA 90095, USA.ORCID 0000-0002-8460-8616

Funding

Mitochondrial biogenesis, genetics and cell loss in mammalian agingR01AG055518 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AIKEN, JUDD M., HERBST, ALLEN · 2017 to 2022
$2.0M
Mitochondrial DNA Deletion Mutations: Biomarkers of AgingR56AG060880 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AIKEN, JUDD M., ALLISON, DAVID B · 2018 to 2018
$574k
Quantitative imaging of the dystrophin-glycoprotein complexR21AR072950 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOBLE, PHILIP, WANAGAT, JONATHAN · 2019 to 2020
$357k
NIAMS NIH HHS R21 AR072950NIA NIH HHS R01 AG055518NIA NIH HHS R56 AG060880
6 · The paper itself

Abstract

"The main conclusions are that the ageing atrophy begins as early as around 25 years of age and thereafter accelerates and, for this muscle, is caused mainly by a loss of fibers and to a lesser extent by a reduction in fiber size [...].

Indexed as

MitochondriaNeuromuscular JunctionCellular SenescenceMuscles

Identifiers

PMID32751058
PMCPMC7464736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.