Evidence map›Paper›PMID 32750928›Full record

ArticleIEEE journal of biomedical and health informatics2021

Upper Esophageal Sphincter Opening Segmentation With Convolutional Recurrent Neural Networks in High Resolution Cervical Auscultation.

Yassin Khalifa, Cara Donohue, James L Coyle, Ervin Sejdic

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in IEEE journal of biomedical and health informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04468191 (Quantifying Fatigue of the Respiratory and Swallowing Musculature in Patients With Amyotrophic Lateral Sclerosis), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04468191 nawithdrawnnot on this map

Quantifying Fatigue of the Respiratory and Swallowing Musculature in Patients With Amyotrophic Lateral Sclerosis

TypeinterventionalSponsorCara DonohueRan2021 to 2021Enrolled0ConditionsAmyotrophic Lateral Sclerosis, Dysphagia, Dyspnea, Respiration DisordersArmsExperimental expiratory muscle strength training (EMST), Sham expiratory muscle strength training (EMST)
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  7. Article
  8. Review
  9. Article
  10. A Review of Recurrent Neural Network-Based Methods in Computational Physiology.IEEE transactions on neural networks and learning systems · 2023
    Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yassin Khalifa
Cara Donohue
James L Coyle
Ervin Sejdic
University of Pittsburgh · US

Funding

The Aspirometer: A noninvasive tool to detect swallowing safety and efficiencyR01HD074819 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COYLE, JAMES L, SEJDIC, ERVIN · 2013 to 2022
$3.0M
Instrumental screening for dysphagia by combining high-resolution cervical auscultation with advanced data analysis tools to identify silent dysphagia and silent aspirationR01HD092239 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COYLE, JAMES L · 2017 to 2020
$1.2M
NICHD NIH HHS R01 HD074819NICHD NIH HHS R01 HD092239
6 · The paper itself

Abstract

Upper esophageal sphincter is an important anatomical landmark of the swallowing process commonly observed through the kinematic analysis of radiographic examinations that are vulnerable to subjectivity and clinical feasibility issues. Acting as the doorway of esophagus, upper esophageal sphincter allows the transition of ingested materials from pharyngeal into esophageal stages of swallowing and a reduced duration of opening can lead to penetration/aspiration and/or pharyngeal residue. Therefore, in this study we consider a non-invasive high resolution cervical auscultation-based screening tool to approximate the human ratings of upper esophageal sphincter opening and closure. Swallows were collected from 116 patients and a deep neural network was trained to produce a mask that demarcates the duration of upper esophageal sphincter opening. The proposed method achieved more than 90% accuracy and similar values of sensitivity and specificity when compared to human ratings even when tested over swallows from an independent clinical experiment. Moreover, the predicted opening and closure moments surprisingly fell within an inter-human comparable error of their human rated counterparts which demonstrates the clinical significance of high resolution cervical auscultation in replacing ionizing radiation-based evaluation of swallowing kinematics.

Indexed as

DeglutitionEsophageal Sphincter, UpperAuscultationHumansManometryNeural Networks, Computer

Identifiers

PMID32750928
PMCPMC7714702
OpenAlexW3033575927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.