Evidence map›Paper›PMID 32750488›Full record

ArticleJournal of cardiac failure2020

Pulmonary Vascular Pressures and Gas Exchange Response to Exercise in Heart Failure With Preserved Ejection Fraction.

Caitlin C Fermoyle, Glenn M Stewart, Barry A Borlaug, Bruce D Johnson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cardiac failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Caitlin C FermoyleDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Glenn M StewartDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Barry A BorlaugDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Bruce D JohnsonDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address: johnson.bruce@mayo.edu.
Mayo Clinic · US

Funding

Pulmonary Limitations in Chronic Heart FailureR01HL071478 · NHLBI · MAYO CLINIC ROCHESTER · PI JOHNSON, BRUCE D · 2002 to 2014
$3.7M
Mayo Heart Failure Regional Clinical CenterU10HL110262 · NHLBI · MAYO CLINIC ROCHESTER · PI REDFIELD, MARGARET M · 2012 to 2018
$3.6M
HL-Inorganic Nitrite to Enhance Benefits from Exercise Training in Heart Failure with preserved Ejection FractionR01HL128526 · NHLBI · MAYO CLINIC ROCHESTER · PI BORLAUG, BARRY A. · 2016 to 2019
$2.4M
NHLBI NIH HHS R01 HL071478NHLBI NIH HHS R01 HL128526NHLBI NIH HHS U10 HL110262
6 · The paper itself

Abstract

Elevated left ventricular filling pressure (measured as mean pulmonary capillary wedge pressure) at rest or with exercise is diagnostic of heart failure with preserved ejection fraction. However, the capacity of the right ventricle to compensate for a high mean pulmonary capillary wedge pressure and thus maintain an appropriate transpulmonary gradient (TPG) and perfusion of the pulmonary capillaries is likely an important contributor to gas exchange efficiency and exercise capacity. Therefore, this study aimed to determine whether a higher TPG at peak exercise is associated with superior exercise capacity and gas exchange. Gas exchange data from dyspneic patients referred for exercise right heart catheterization were retrospectively analyzed and patients were split into two groups based on TPG. Patients with a higher TPG at peak exercise had a higher peak VO

Indexed as

Heart FailureExercise TestExercise ToleranceHumansOxygen ConsumptionPulmonary Gas ExchangeRetrospective StudiesStroke Volumecardiopulmonary exercise testexercise intoleranceright heart catheterizationTranspulmonary gradient

Identifiers

PMID32750488
PMCPMC7704759
OpenAlexW3046768771

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.