Evidence map›Paper›PMID 32749905›Full record

ReviewExpert review of anti-infective therapy2020

Quorum quenching enzymes and their effects on virulence, biofilm, and microbiomes: a review of recent advances.

Rakesh Sikdar, Mikael Elias

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of anti-infective therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 192 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Characterization of a Novel Quorum QuencherPlants (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Diversity and evolution of quorum-sensing systems inFrontiers in bioinformatics · 2026
    Article
  16. Review
  17. Review
  18. Review
  19. Quenching corrinoid-based interactions in a model bacterial coculture.bioRxiv : the preprint server for biology · 2026
    Article
  20. Antibacterial and Antibiofilm Activities of Bluestem (International journal of microbiology · 2026
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rakesh SikdarBiochemistry, Molecular Biology & Biophysics Department and BioTechnology Institute, University of Minnesota , Saint Paul, Minnesota, USA.
Mikael EliasBiochemistry, Molecular Biology & Biophysics Department and BioTechnology Institute, University of Minnesota , Saint Paul, Minnesota, USA.ORCID 0000-0003-0406-7539
University of Minnesota · US

Funding

Unravelling the Importance of Bacterial Signaling using Specific Interference StrategiesR35GM133487 · NIGMS · UNIVERSITY OF MINNESOTA · PI Mikael H Elias · 2019 to 2026
$2.7M
NIGMS NIH HHS R35 GM133487
6 · The paper itself

Abstract

introductionNumerous bacterial behaviors are regulated by a cell-density dependent mechanism known as Quorum Sensing (QS). QS relies on communication between bacterial cells using diffusible signaling molecules known as autoinducers. QS regulates physiological processes such as metabolism, virulence, and biofilm formation. Quorum Quenching (QQ) is the inhibition of QS using chemical or enzymatic means to counteract behaviors regulated by QS. AREAS COVERED: We examine the main, diverse QS mechanisms present in bacterial species, with a special emphasis on AHL-mediated QS. We also discuss key EXPERT OPINION: Enabled

Indexed as

BiofilmsAnimalsBacteriaHumansMicrobiotaQuorum SensingVirulencelactonasemicrobiomeQuorum quenching (QQ)Quorum sensing (QS)signaling

Identifiers

PMID32749905
PMCPMC7705441
OpenAlexW3047600906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.