Evidence map›Paper›PMID 32749877›Full record

Trial reportAIDS education and prevention : official publication of the International Society for AIDS Education2020

Understanding of Perceived Infectiousness and Its Influence on Sexual Behavior Among Individuals With Acute HIV Infection in Lilongwe, Malawi (HPTN 062).

Tiarney D Ritchwood, Cecilia Massa, Gift Kamanga, Audrey Pettifor, Irving Hoffman, Amy Corneli

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS education and prevention : official publication of the International Society for AIDS Education, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Psychosocial Phenotype and Risky Sexual Behavior Among People Living with HIV in Changsha: A Latent Profile Analysis.International journal of sexual health : official journal of the World Association for Sexual Health · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tiarney D RitchwoodDepartment of Family Medicine and Community Health, School of Medicine, Duke University, Durham, North Carolina.
Cecilia MassaUNC Project Lilongwe, Lilongwe, Malawi.
Gift KamangaFHI 360, Lilongwe, Malawi.
Audrey PettiforDepartment of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Irving HoffmanDivision of Infectious Diseases, University of North Carolina at Chapel Hill.
Amy CorneliDepartment of Population Health Sciences, School of Medicine, Duke University, and the Duke Clinical Research Institute, Duke University.
University of North Carolina at Chapel Hill · USDuke University · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
University of North Carolina Global HIV Prevention and Treatment Clinical Trials Unit 2024 SupplementUM1AI069423 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, MINA CHRISTINE HOSSEINIPOUR · 2012 to 2026
$71.8M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
UCLA Implementation Science and Substance Use Research and Education (ISSURE) ProgramR25DA035692 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIMOTHY W FONG, GAIL E. WYATT · 2013 to 2026
$3.9M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Social support to retain adolescents living with HIV in care and improve ART adherenceK08MH118965 · NIMH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RITCHWOOD, TIARNEY D · 2019 to 2023
$908k
FIC NIH HHS D43 TW009340NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI064518NIAID NIH HHS UM1 AI069423NIDA NIH HHS R25 DA035692NIMH NIH HHS K08 MH118965NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

We implemented HPTN 062, an acceptability and feasibility study of a motivational-interviewing (MI) intervention to reduce HIV transmission among individuals with acute HIV infection (AHI) in Lilongwe, Malawi. Participants were randomly assigned to receive either brief education or the MI intervention over 24 weeks; all participants received the same messages about AHI. We used mixed methods to assess participants' understanding of the association between AHI and viral load, and its connection to sexual behavior at 8 weeks. While most participants understood key aspects of AHI, MI-intervention participants gave substantially more detailed descriptions of their understanding. Nearly all participants, regardless of study arm, understood that they were highly infectious and would be very likely to transmit HIV after unprotected sex during AHI. Our findings suggest that messages about AHI delivered during the period of AHI are likely beneficial for ensuring that those with AHI understand their level of infectiousness and its association with forward transmission.

Indexed as

Motivational InterviewingSexual BehaviorAcute DiseaseAdultAnti-HIV AgentsDisease Transmission, InfectiousFeasibility StudiesFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansMalawiMaleMiddle AgedOutcome Assessment, Health CarePatient Education as TopicAnti-HIV Agentsacute HIVinfectiousnessinterventionmotivational interviewingsexual risk

Identifiers

PMID32749877
PMCPMC8269280
OpenAlexW3047585740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.