ArticleActa ophthalmologica2021
Retinal vessel architecture in retinopathy of prematurity and healthy controls using swept-source optical coherence tomography angiography.
Article in Acta ophthalmologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Normative Optical Coherence Tomography Angiography Metrics of Macular Vessel Density and Foveal Avascular Zone in Healthy Children.Journal of clinical medicine · 2025Article
- The analysis of foveal microvascular anomalies in retinopathy of prematurity after anti-vascular endothelial growth factor therapy using optical coherence tomography angiography.BMC ophthalmology · 2024Article
- Vascular imaging findings in retinopathy of prematurity.Acta ophthalmologica · 2024Review
- Functional OCT reveals anisotropic changes of retinal flicker-evoked vasodilation.Optics letters · 2024Article
- Automated diagnosis of plus disease in retinopathy of prematurity using quantification of vessels characteristics.Scientific reports · 2024Article
- Misalignment of center of foveal avascular zone and center of photoreceptors in eyes with history of retinopathy of prematurity.Scientific reports · 2024Article
- Evaluation of childhood developingWorld journal of clinical cases · 2023Article
- Retinal structure and visual pathway function at school age in children born extremely preterm: a population-based study.BMC ophthalmology · 2023Article
- Optical Coherence Tomography and Optical Coherence Tomography Angiography in Pediatric Retinal Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Evaluation of macular microvascular structure with optical coherence tomography angiography in children with history of treatment for retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Retinal and peripapillary vascular deformations in prematurely born children aged 4-12 years with a history of retinopathy of prematurity.Scientific reports · 2023Article
- The characteristics of dome-shaped macula in Chinese children aged 4-6 years using optical coherence tomography angiography.BMC ophthalmology · 2023Article
- Quantitative measures of the vascular and neural components of the retina in adult individuals with congenital and untreated growth hormone deficiency.International journal of retina and vitreous · 2022Article
- Insights into the developing fovea revealed by imaging.Progress in retinal and eye research · 2022Review
- Optical coherence tomography angiography in healthy children: normative data and age-related changes in microvascular structure of the optic disk and macula.International ophthalmology · 2022Article
- Morphology and Vessel Density of the Macula in Preterm Children Using Optical Coherence Tomography Angiography.Journal of clinical medicine · 2022Article
- Assessment of the retinal vasculature in healthy Chinese preschool children aged 4-6 years old using optical coherence tomography angiography.BMC ophthalmology · 2021Article
- Role of macrophages in fetal development and perinatal disorders.Pediatric research · 2021Review
- Advances in retinopathy of prematurity imaging.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine microvascular changes in children with a history of retinopathy of prematurity (ROP) and in a control group of full-term children.
methodsIn a cross-sectional study, 30 eyes of 15 children aged 6-8 years with a history of ROP were evaluated with swept-source optical coherence tomography angiography (SS-OCTA). Twenty-eight eyes of 22 age-matched full-term children served as a healthy control group. The foveal avascular zone (FAZ), vessel density (VD) and choroidal vascular flow area (VFA) were evaluated on OCTA and correlated with central retinal thickness (CRT), visual acuity (VA), birth weight (BW), gestational age (GA) and ROP stages.
resultsTwenty-two eyes of 14 children with a history of ROP (stage 1-3) and 25 eyes of 19 full-term children were available for evaluation. In the ROP group, the gestational age was 27 ± 2 weeks and birth weight was 781 ± 164 g. In the ROP group, CRT was higher in the central ETDRS segment (mean difference [95% CI]: 32.8 µm [18.7; 47.0], p = 0.0002) compared to the controls. Smaller mean FAZ area (-0.12 [-0.19; -0.04], p = 0.004) and perimeter (-662 [-1228; -96], p = 0.03) was found in comparison to the control group. An oval shape of the FAZ was observed among patients with a history of ROP. The mean central VD of the superficial plexus was 28 ± 8/23 ± 8% and of the deep plexus 7 ± 7/3 ± 5% (ROP group/control group; p > 0.05). No statistically significant difference was found regarding the choroidal VFA. Only weak correlation of FAZ and VD with function was observed.
conclusionsSwept-source optical coherence tomography angiography imaging revealed significant microvascular anomalies in children with a history of ROP indicating disturbance of early morphological development of the central retina.
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