ReviewCurrent gastroenterology reports2020
Low Anterior Resection Syndrome.
Review in Current gastroenterology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05016583 (Paula Method Muscle Exercises in Patients With Low Anterior Resection Syndrome After Sphincter Sparing Rectal Resection), which is not on this map. Cited by 45 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Paula Method Muscle Exercises in Patients With Low Anterior Resection Syndrome After Sphincter Sparing Rectal Resection: A Feasibility Study
Who cites it
45 citing papers in PubMed, 5 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- The efficacy of retrograde and antegrade enemas in the management of low anterior resection syndrome in patients undergoing rectal resection: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Systematic review of the management options available for low anterior resection syndrome (LARS).Techniques in coloproctology · 2025Pooled it
- Efficacy and safety of transanal endoscopic microsurgery for early rectal cancer: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Comparison of complications and bowel function among different reconstruction techniques after low anterior resection for rectal cancer: a systematic review and network meta-analysis.World journal of surgical oncology · 2023Pooled it
- Safety and efficacy of side-to-end anastomosis versus colonic J-pouch anastomosis in sphincter-preserving resections: an updated meta-analysis of randomized controlled trials.World journal of surgical oncology · 2021Pooled it
- Effects of a Psycho-Behavioural Intervention on Cancer-Related Fatigue Among Patients With Colorectal Cancer: A Pilot Randomised Controlled Trial.Psycho-oncology · 2026Trial
- A multicentre prospective study of anal function after laparoscopic ultra-low rectal cancer surgery using a mixed-effects model.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Trial
- Preservation of inferior mesenteric artery reduces short- and long-term defecatory dysfunction after laparoscopic colorectal resection for diverticular disease: An RCT.Surgical endoscopy · 2025Trial
- Effectiveness of personalized treatment stage-adjusted digital therapeutics in colorectal cancer: a randomized controlled trial.BMC cancer · 2023Trial
- Quality of life among colorectal cancer survivors participating in a pilot randomized controlled trial of a web-based dietary intervention with text messages.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Effect of 3D Animation Combined with Teach-Back Health Education on Pelvic Floor Muscle Training in LARS Patients: A Randomized Controlled Trial.Journal of nursing management · 2023Trial
- Association of dietary habits and physical activity with the severity of fecal incontinence in patients with colorectal cancer after minimally invasive surgery: An exploratory study.Asia-Pacific journal of oncology nursing · 2026Article
- Patient-reported outcomes in low anterior resection syndrome: a comparison of open and robotic surgery.International journal of colorectal disease · 2026Article
- Impact of surgical approach and anastomosis distance on low anterior resection syndrome.BMC surgery · 2026Article
- Short Distal Resection Margin Does Not Increase Recurrence Risk After R0 Resection for Rectal Neuroendocrine Tumors: A Single-Institution Retrospective Study of 208 Patients.Annals of gastroenterological surgery · 2026Article
- Association Between Radiotherapy (±Chemotherapy) and the Severity of Low Anterior Resection Syndrome After Rectal Cancer Surgery: Does Radiotherapy Separate Risk?Medical sciences (Basel, Switzerland) · 2026Observational
- Laparoscopic Resection Rectopexy with Transanal Specimen Extraction for Complete Rectal Prolapse: Retrospective Cohort Study of Functional Outcomes.Journal of clinical medicine · 2026Article
- Case Report: Quantitative and qualitative evaluation for electroacupuncture combined with moxibustion in the treatment of recalcitrant low anterior resection syndrome.Frontiers in medicine · 2026Article
- Efficacy and safety of the traditional Chinese medicine formulation BL-1 for the treatment of low anterior resection syndrome: study protocol for a double-blind, randomized, placebo-controlled trial.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026Article
- Organ preservation after neoadjuvant immunotherapy in mismatch repair-deficient colorectal cancer: response assessment, watch-and-wait, and salvage surgery.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewLow anterior resection syndrome is a highly prevalent condition that can develop after anal sphincter-sparing surgery for rectal cancer and impair quality of life. In this review, we summarize the major features and pathophysiology of this syndrome and discuss treatment approaches. RECENT
findingsQuality of life correlates significantly with severity of low anterior resection syndrome. Prompt assessment and initiation of therapy are essential to rehabilitating damaged mechanical and neural structures. Anorectal manometry demonstrates a global decrease in sphincteric function postoperatively, though in many patients, function does recover. Transanal irrigation, pelvic floor rehabilitation, and biofeedback are the mainstays of the treatment of major LARS. Definitive stoma can be considered in therapy refractory LARS > 2 years. The development of low anterior resection syndrome likely involves an interplay between mechanical and neural pathways. Clinically, patients present at varying levels of severity, and scoring systems are available to help assess patient symptoms and guide therapy. Treatment approaches range from conservative therapies to biofeedback and sacral nerve stimulation. Future randomized controlled trials aimed at risk stratification of patients and development of severity-based treatment algorithms are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.