Evidence map›Paper›PMID 32749573›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2020

Insights on Zika virus envelope gene conservation in American outbreaks.

Mateus V Thomazella, Quirino A Lima Neto, Francisco F Duarte Junior, Fernando A Jorge, Déborah de Castro Moreira, Amauri D Leal Junior, Mayra M Presibella, Irina N Riediger, Rafael A da Silva, Isabel Maria V G de Carvalho and 1 more

Open access · greenAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Mateus V ThomazellaLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil. thomazella16@gmail.com.ORCID http://orcid.org/0000-0002-1527-6910
Quirino A Lima NetoLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
Francisco F Duarte JuniorLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
Fernando A JorgeLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
Déborah de Castro MoreiraLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
Amauri D Leal JuniorLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
Mayra M PresibellaLaboratório Central do Estado do Paraná - LACEN-PR, Curitiba, Paraná, Brazil.
Irina N RiedigerLaboratório Central do Estado do Paraná - LACEN-PR, Curitiba, Paraná, Brazil.
Rafael A da SilvaInstituto Butantan, São Paulo, São Paulo, Brazil.
Isabel Maria V G de CarvalhoInstituto Butantan, São Paulo, São Paulo, Brazil.
Dennis A BertoliniLaboratório de Virologia Clínica, Universidade Estadual de Maringá - UEM, Avenida Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
Universidade Estadual de Maringá · BRInstituto Butantan · BRInstituto de Tecnologia do Paraná · BR

Funding

Fundação Araucária 040/2016
6 · The paper itself

Abstract

Phylogenetic studies with Zika virus (ZIKV) have been conducted in Brazil. In this study, we sequenced 8 new sequences of the ZIKV envelope (E) gene from strains of cases from the Paraná and Mato Grosso do Sul states in 2016. A low phylogenetic signal was observed, with more than 40% of unresolved quartets, and the Maximum Likelihood Tree grouped all sequences in the Brazilian branches within the Asian genotype. In addition, a Shannon entropy analysis was conducted, showing a high stability in the E protein through the ZIKV polyprotein. Taken together, these results suggest a high degree of conservation in the ZIKV E gene from the recent American outbreaks.

Indexed as

Disease OutbreaksBrazilGenes, ViralGenome, ViralGenotypeHumansViral EnvelopeViral Envelope ProteinsZika VirusZika Virus InfectionViral Envelope ProteinsBrazilEntropyPhylogenetic studyZika virus

Identifiers

PMID32749573
PMCPMC7688768
OpenAlexW3047130388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.