Evidence map›Paper›PMID 32749530›Full record

ArticlePediatric radiology2020

Thoracic imaging of coronavirus disease 2019 (COVID-19) in children: a series of 91 cases.

Pablo Caro-Dominguez, Susan Cheng Shelmerdine, Seema Toso, Aurelio Secinaro, Paolo Toma, Maria Beatrice Damasio, María Navallas, Lucia Riaza-Martin, David Gomez-Pastrana, Maryam Ghadimi Mahani and 17 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Pediatric radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
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  9. SARS-CoV-2 Infection and COVID-19 in Children.Clinics in chest medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 15 countries.

Pablo Caro-DominguezUnidad de Radiologia Pediatrica, Servicio de Radiologia, Hospital Universitario Virgen del Rocio, Avenida Manuel Siurot s/n, CP 41013, Sevilla, Spain. pablocaro82@hotmail.com.ORCID 0000-0003-3540-6580
Susan Cheng ShelmerdineDepartment of Clinical Radiology, Great Ormond Street Hospital for Children, NHS Trust, London, UK.
Seema TosoDepartment of Diagnostics, Pediatric Radiology, Geneva Children's Hospitals, Geneva, Switzerland.
Aurelio SecinaroDepartment of Imaging, IRCCS Ospedale Pediatrico Bambino Gesu, Rome, Italy.
Paolo TomaDepartment of Imaging, IRCCS Ospedale Pediatrico Bambino Gesu, Rome, Italy.
Maria Beatrice DamasioU.O.C. Radiologia, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
María NavallasRadiología Pediátrica, Servicio de Radiología, Hospital Universitario 12 de Octubre, Madrid, Spain.
Lucia Riaza-MartinRadiología Pediátrica, Servicio de Radiología, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
David Gomez-PastranaNeumología Pediátrica, Servicio de Pediatría, Hospital Universitario Jerez de la Frontera, Cádiz, Spain.
Maryam Ghadimi MahaniSection of Pediatric Radiology, C. S. Mott Children's Hospital, Department of Radiology, Michigan Medicine, Ann Arbor, MI, USA.
Sarah M DesokyDepartment of Medical Imaging, University of Arizona College of Medicine, Tucson, AZ, USA.
Carlos F Ugas CharcapeDepartment of Imaging, Instituto Nacional de Salud del Niño San Borja, Lima, Peru.
Judith Almanza-ArandaImaging Department, Hospital Infantil de México Federico Gómez, Ciudad de México, Mexico.
Maria Elena UcarRadiologia Pediatrica, Sor Maria Ludovica Children's Hospital, La Plata, Argentina.
Jovan LovrenskiFaculty of Medicine Novi Sad, University of Novi Sad, Institute for Children and Adolescents Health Care of Vojvodina, Novi Sad, Serbia.
Sureyya Burcu GorkemPaediatric Radiology Section, Children's Hospital Department of Radiology, Kayseri, Turkey.
Efthymia AlexopoulouPaediatric Radiology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Pierluigi CietDepartment of Radiology and Nuclear Medicine, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, The Netherlands.
Joost van SchuppenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Hubert Ducou le PointeImaging Department, Trousseau Hospital, AP-HP, Sorbonne University, Paris, France.
Hyun Woo GooDepartment of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Christian J KellenbergerDiagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland.
Maria RaissakiDepartment of Radiology, University Hospital of Heraklion, University of Crete, Crete, Greece.
Catherine M OwensDepartment of Clinical Radiology, Great Ormond Street Hospital for Children, NHS Trust, London, UK.
Franz Wolfgang HirschPaediatric Radiology, University Hospital of Leipzig, Leipzig, Germany.
Rick R van RijnDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Collaborators of the European Society of Paediatric Radiology Cardiothoracic Task Force
Amsterdam University Medical Centers · NLBambino Gesù Children's Hospital · ITInstituto Nacional de Salud del Niño · PEQatar Airways (Qatar) · QAErasmus MC - Sophia Children’s Hospital · NLGreat Ormond Street Hospital · GBHospital de Niños Superiora Sor María Ludovica · ARHospital Infantil de México Federico Gómez · MXHospital Jerez Puerta del Sur · ESHospital Universitario 12 De Octubre · ESHospital Universitario Virgen del Rocío · ESIstituto Giannina Gaslini · ITMichigan Medicine · USNational and Kapodistrian University of Athens · GRSorbonne Université · FRUlsan College · KRUniversity Children's Hospital Zurich · CHUniversity Hospital Leipzig · DEUniversity Hospital of Geneva · CHUniversity of Arizona · US

Funding

Department of Health CDF-2017-10-037Medical Research Council MR/R002118/1
6 · The paper itself

Abstract

backgroundPulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic.

objectiveTo collect paediatric COVID-19 cases worldwide and to summarize both clinical and imaging findings in children who tested positive on polymerase chain reaction testing for SARS-CoV-2. MATERIALS AND

methodsData were collected by completion of a standardised case report form submitted to the office of the European Society of Paediatric Radiology from March 12 to April 8, 2020. Chest imaging findings in children younger than 18 years old who tested positive on polymerase chain reaction testing for SARS-CoV-2 were included. Representative imaging studies were evaluated by multiple senior paediatric radiologists from this group with expertise in paediatric chest imaging.

resultsNinety-one children were included (49 males; median age: 6.1 years, interquartile range: 1.0 to 13.0 years, range: 9 days-17 years). Most had mild symptoms, mostly fever and cough, and one-third had coexisting medical conditions. Eleven percent of children presented with severe symptoms and required intensive unit care. Chest radiographs were available in 89% of patients and 10% of them were normal. Abnormal chest radiographs showed mainly perihilar bronchial wall thickening (58%) and/or airspace consolidation (35%). Computed tomography (CT) scans were available in 26% of cases, with the most common abnormality being ground glass opacities (88%) and/or airspace consolidation (58%). Tree in bud opacities were seen in 6 of 24 CTs (25%). Lung ultrasound and chest magnetic resonance imaging were rarely utilized.

conclusionIt seems unnecessary to perform chest imaging in children to diagnose COVID-19. Chest radiography can be used in symptomatic children to assess airway infection or pneumonia. CT should be reserved for when there is clinical concern to assess for possible complications, especially in children with coexisting medical conditions.

Indexed as

BetacoronavirusAdolescentChildChild, PreschoolCoronavirus InfectionsCOVID-19FemaleHumansInfantInfant, NewbornLungMalePandemicsPneumonia, ViralRadiography, ThoracicReproducibility of ResultsChildrenComputed tomographyCoronavirusCOVID-19ImagingLower respiratory tract infectionPneumonitisRadiography

Identifiers

PMID32749530
PMCPMC7399600
OpenAlexW3047271507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.