Evidence map›Paper›PMID 32749218›Full record

ArticleeLife2020

A flexible framework for simulating and fitting generalized drift-diffusion models.

Maxwell Shinn, Norman H Lam, John D Murray

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Trial
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  10. Neural correlates of perceptual decision-making in the primary somatosensory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  11. Review
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  18. Learning expectations shape cognitive control allocation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maxwell Shinn *Department of Psychiatry, Yale University, New Haven, United States.ORCID 0000-0002-7424-4230
Norman H Lam *Department of Physics, Yale University, New Haven, United States.ORCID 0000-0001-5817-6680
John D MurrayDepartment of Psychiatry, Yale University, New Haven, United States.ORCID 0000-0003-4115-8181

Funding

Linking Large-Scale Dysconnectivity in Schizophrenia to Cortical Circuit Function at the Individual Level through Computational Modeling and Multimodal NeuroimagingR01MH112746 · NIMH · YALE UNIVERSITY · PI MURRAY, JOHN DAVID · 2017 to 2020
$1.7M
NIMH NIH HHS R01 MH112746NSERC PGSD2-502866-2017
6 · The paper itself

Abstract

The drift-diffusion model (DDM) is an important decision-making model in cognitive neuroscience. However, innovations in model form have been limited by methodological challenges. Here, we introduce the generalized drift-diffusion model (GDDM) framework for building and fitting DDM extensions, and provide a software package which implements the framework. The GDDM framework augments traditional DDM parameters through arbitrary user-defined functions. Models are solved numerically by directly solving the Fokker-Planck equation using efficient numerical methods, yielding a 100-fold or greater speedup over standard methodology. This speed allows GDDMs to be fit to data using maximum likelihood on the full response time (RT) distribution. We demonstrate fitting of GDDMs within our framework to both animal and human datasets from perceptual decision-making tasks, with better accuracy and fewer parameters than several DDMs implemented using the latest methodology, to test hypothesized decision-making mechanisms. Overall, our framework will allow for decision-making model innovation and novel experimental designs.

Indexed as

Decision MakingModels, NeurologicalModels, PsychologicalSoftwareAnimalsData AnalysisHumanscomputational modeldecision makingdrift-diffusion modelmodel fittingneurosciencenonepsychophysicsresponse time

Identifiers

PMID32749218
PMCPMC7462609

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.