Evidence map›Paper›PMID 32749216›Full record

ArticleeLife2020

Tuning of olfactory cortex ventral tenia tecta neurons to distinct task elements of goal-directed behavior.

Kazuki Shiotani, Yuta Tanisumi, Koshi Murata, Junya Hirokawa, Yoshio Sakurai, Hiroyuki Manabe

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  10. An Emergent Population Code in Primary Auditory Cortex Supports Selective Attention to Spectral and Temporal Sound Features.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kazuki Shiotani *Laboratory of Neural Information, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.ORCID 0000-0001-5596-5609
Yuta Tanisumi *Laboratory of Neural Information, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.
Koshi MurataLaboratory of Neural Information, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.
Junya HirokawaLaboratory of Neural Information, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.ORCID 0000-0003-1238-5713
Yoshio SakuraiLaboratory of Neural Information, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.
Hiroyuki ManabeLaboratory of Neural Information, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.ORCID 0000-0002-3910-4849
Doshisha University · JPUniversity of Fukui · JP

Funding

Japan Society for the Promotion of Science Grant-in-Aid for Challenging Exploratory Research 16K14557Japan Society for the Promotion of Science Grant-in-Aid for JSPS Fellows 18J21358Japan Society for the Promotion of Science Grant-in-Aid for JSPS Fellows 19J20733Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research(A) 16H02061Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research on Innovative Areas 18H05088Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research on Innovative Areas 25135708
6 · The paper itself

Abstract

The ventral tenia tecta (vTT) is a component of the olfactory cortex and receives both bottom-up odor signals and top-down signals. However, the roles of the vTT in odor-coding and integration of inputs are poorly understood. Here, we investigated the involvement of the vTT in these processes by recording the activity from individual vTT neurons during the performance of learned odor-guided reward-directed tasks in mice. We report that individual vTT cells are highly tuned to a specific behavioral epoch of learned tasks, whereby the duration of increased firing correlated with the temporal length of the behavioral epoch. The peak time for increased firing among recorded vTT cells encompassed almost the entire temporal window of the tasks. Collectively, our results indicate that vTT cells are selectively activated during a specific behavioral context and that the function of the vTT changes dynamically in a context-dependent manner during goal-directed behaviors.

Indexed as

OdorantsOlfactory PerceptionRewardSmellAnimalsLearningMaleMiceMice, Inbred C57BLOlfactory CortexRandom Allocationelectrophysiologymouseneuroscienceolfactory cortextenia tecta

Identifiers

PMID32749216
PMCPMC7423337
OpenAlexW3046927724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.