Evidence map›Paper›PMID 32748982›Full record

ArticleClinical transplantation2020

Evaluating resilience as a predictor of outcomes in lung transplant candidates.

Yvonne Tran Bui, Matthew A Hathcock, Roberto P Benzo, Marie M Budev, Satish Chandrashekaran, David B Erasmus, Erika D Lease, Deborah J Levine, Karin L Thompson, Bradley K Johnson and 2 more

Abstract read
In one paragraph

Article in Clinical transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Barriers to Immunosuppressant Medication Adherence in Thoracic Transplant Recipients: Initial Findings.International journal of environmental research and public health · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yvonne Tran BuiMayo Clinic Alix School of Medicine, Rochester, Minnesota, USA.ORCID 0000-0002-7414-2461
Matthew A HathcockBiomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Roberto P BenzoDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Marie M BudevDivision of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Satish ChandrashekaranDivision of Pulmonary, Critical Care & Sleep Medicine, University of Florida, Gainesville, Florida, USA.
David B ErasmusTransplant Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Erika D LeaseDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, Washington, USA.
Deborah J LevineDivision of Pulmonary and Critical Care Medicine, University of Texas Health, San Antonio, Texas, USA.
Karin L ThompsonPulmonary Clinical Research Unit, Mayo Clinic, Rochester, Minnesota, USA.
Bradley K JohnsonBiomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Sheila G Jowsey-GregoireDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, Minnesota, USA.
Cassie C KennedyDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-3219-165X

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Exploring the Unmeasured Risk and Treating the Untreated Prognostic Factor: Towards Candidate Optimization in Heart and Lung TransplantK23HL128859 · NHLBI · MAYO CLINIC ROCHESTER · PI KENNEDY, CASSIE COLLEEN · 2016 to 2020
$854k
Mechanistic Effects of Health Coaching to reduce COPD HospitalizationsK24HL138150 · NHLBI · MAYO CLINIC ROCHESTER · PI BENZO, ROBERTO PABLO · 2018 to 2022
$602k
NCATS NIH HHS UL1 TR002377NHLBI NIH HHS K23 HL128859NHLBI NIH HHS K24 HL138150
6 · The paper itself

Abstract

backgroundResilience represents the capacity to adapt to adversity. Resilience can improve following behavioral interventions. We examined lung transplant candidates' resilience as a novel predictor using the Connor-Davidson Resilience Scale (RISC-10).

methodsWaitlisted candidates at six centers were mailed questionnaires from 9/16/2015 to 10/1/2019. Follow-up surveys were collected annually and post-transplant. Outcomes were recorded through February 17, 2020. Primary outcome was pre-transplant death/delisting. Analyses included t test or chi-square for group comparisons, Pearson's correlation coefficients for strength of relationships, and Cox proportional-hazard models to evaluate associations with outcomes, adjusting for age, sex, and mood.

resultsParticipation was 55.3% (N = 199). Baseline RISC-10 averaged 32.0 ± 5.6 and did not differ by demographics, primary transplant diagnosis, or disease severity markers. RISC-10 did not correlate to the commonly utilized Psychosocial Assessment of Candidates for Transplant [PACT] or Stanford Integrated Psychosocial Assessment for Transplantation [SIPAT] tools. Scores < 26.3 (representing > 1 standard deviation below population average) occurred in 16% and were associated with pre-transplant death or delisting, adjusted Hazard Ratio of 2.60 (95% Confidence Interval 1.23-5.77; P = .01).

conclusionOne in six lung candidates had low resilience, predicting increased pre-transplant death/delisting. RISC-10 did not correlate with PACT or SIPAT; resilience may represent a novel risk factor.

Indexed as

Lung TransplantationHumansProportional Hazards ModelsRisk FactorsSurveys and Questionnaireslung transplantationmental healthpsychological resilience

Identifiers

PMID32748982
PMCPMC7722186

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.