Evidence map›Paper›PMID 32748812›Full record

ArticleInternational journal of environmental research and public health2020

Evidence-Based Considerations Exploring Relations between SARS-CoV-2 Pandemic and Air Pollution: Involvement of PM2.5-Mediated Up-Regulation of the Viral Receptor ACE-2.

Marina Borro, Paolo Di Girolamo, Giovanna Gentile, Ottavia De Luca, Robert Preissner, Adriano Marcolongo, Stefano Ferracuti, Maurizio Simmaco

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Mechanisms, Techniques and Devices of Airborne Virus Detection: A Review.International journal of environmental research and public health · 2023
    Review
  8. Air pollution and respiratory infections: the past, present, and future.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Local and transboundary impacts of PMAtmospheric pollution research · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Marina BorroLaboratory of Clinical Biochemistry, University Hospital Sant'Andrea, Department of Neurosciences, Mental Health and Sensory Organs, Faculty of Medicine and Psychology, Sapienza University, via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0002-7839-9125
Paolo Di GirolamoSchool of Engineering, University of Basilicata, viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-7420-3164
Giovanna GentileLaboratory of Clinical Biochemistry, University Hospital Sant'Andrea, Department of Neurosciences, Mental Health and Sensory Organs, Faculty of Medicine and Psychology, Sapienza University, via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0001-8667-3094
Ottavia De LucaLaboratory of Clinical Biochemistry, University Hospital Sant'Andrea, via di Grottarossa 1035, 00189 Rome, Italy.
Robert PreissnerStructural Bioinformatics Group, Charité-Universitätsmedizin Berlin, Philippstr. 12, 10115 Berlin, Germany.ORCID 0000-0002-2407-1087
Adriano MarcolongoGeneral Direction, University Hospital Sant'Andrea, via di Grottarossa 1035, 00189 Rome, Italy.
Stefano FerracutiDepartment of Human Neuroscience, Sapienza University, Piazzale Aldo Moro, 5, 00185 Rome, Italy.ORCID 0000-0003-1150-1460
Maurizio SimmacoLaboratory of Clinical Biochemistry, University Hospital Sant'Andrea, Department of Neurosciences, Mental Health and Sensory Organs, Faculty of Medicine and Psychology, Sapienza University, via di Grottarossa 1035, 00189 Rome, Italy.
Azienda Ospedaliera Sant'Andrea · ITCTO Andrea Alesini · ITCharité - Universitätsmedizin Berlin · DESapienza University of Rome · ITUniversity of Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19/SARS-CoV-2 pandemic struck health, social and economic systems worldwide, and represents an open challenge for scientists -coping with the high inter-individual variability of COVID-19, and for policy makers -coping with the responsibility to understand environmental factors affecting its severity across different geographical areas. Air pollution has been warned of as a modifiable factor contributing to differential SARS-CoV-2 spread but the biological mechanisms underlying the phenomenon are still unknown. Air quality and COVID-19 epidemiological data from 110 Italian provinces were studied by correlation analysis, to evaluate the association between particulate matter (PM)

Indexed as

Air PollutionAngiotensin-Converting Enzyme 2Base SequenceBetacoronavirusCoronavirus InfectionsCOVID-19HumansItalyPandemicsParticulate MatterPeptidyl-Dipeptidase APneumonia, ViralPromoter Regions, GeneticReceptors, VirusSARS-CoV-2Up-RegulationACE2 protein, humanAngiotensin-Converting Enzyme 2Particulate MatterPeptidyl-Dipeptidase AReceptors, Virusangiotensin-converting enzyme 2aryl hydrocarbon receptorCOVID-19PM2.5SARS-CoV-2xenobiotic response element

Identifiers

PMID32748812
PMCPMC7432777
OpenAlexW3046301624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.