Evidence map›Paper›PMID 32748808›Full record

ArticleBiomedicines2020

Organoarsenic Compounds with In Vitro Activity against the Malaria Parasite

Sofia Basova, Nathalie Wilke, Jan Christoph Koch, Aram Prokop, Albrecht Berkessel, Gabriele Pradel, Che Julius Ngwa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sofia BasovaDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Nathalie WilkeDepartment of Paediatric Oncology, Children's Hospital Cologne, Amsterdamer Straße 59, 50735 Cologne, Germany.
Jan Christoph KochDepartment of Chemistry, Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany.
Aram ProkopDepartment of Paediatric Oncology, Children's Hospital Cologne, Amsterdamer Straße 59, 50735 Cologne, Germany.
Albrecht BerkesselDepartment of Chemistry, Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany.ORCID 0000-0003-0470-7428
Gabriele PradelDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Che Julius NgwaDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
RWTH Aachen University · DEUniversity of Cologne · DEHelios Hospital Schwerin · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid development of parasite drug resistance as well as the lack of medications targeting both the asexual and the sexual blood stages of the malaria parasite necessitate the search for novel antimalarial compounds. Eleven organoarsenic compounds were synthesized and tested for their effect on the asexual blood stages and sexual transmission stages of the malaria parasite

Indexed as

antimalarialgametocytocidalmalariaorganoarsenic compoundPlasmodium falciparumtransmission

Identifiers

PMID32748808
PMCPMC7459655
OpenAlexW3046751095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.