Evidence map›Paper›PMID 32748647›Full record

ArticleCartilage2021

Comparative Evaluation of Synovial Multipotent Stem Cells and Meniscal Chondrocytes for Capability of Fibrocartilage Reconstruction.

Jisoo Lee, Seoyoung Jang, JunPyo Kwon, Tong In Oh, EunAh Lee

Open access · bronzeAbstract read
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jisoo LeeDepartment of Medical Engineering, Graduate School, Kyung Hee University, Seoul, South Korea.
Seoyoung JangDepartment of Medical Engineering, Graduate School, Kyung Hee University, Seoul, South Korea.
JunPyo KwonDepartment of Medical Engineering, Graduate School, Kyung Hee University, Seoul, South Korea.
Tong In OhDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, Seoul, South Korea.
EunAh LeeImpedance Imaging Research Center, Kyung Hee University, Seoul, South Korea.ORCID 0000-0003-1208-8807
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMeniscus tissue is composed of highly aligned type I collagen embedded with cartilaginous matrix. This histological feature endows mechanical properties, such as tensile strength along the direction of the collagen alignment and endurance to compressive load induced by weight bearing. The main objective of this study was to compare the fibrocartilage construction capability of different cell sources in the presence of mechanical stimuli.

designSynovial multipotent stem cells (SvMSCs) and meniscal chondrocytes (MCs) from immature and mature rabbits were maintained under similar conditions for comparative evaluation of growth characteristics and senescence tendency. The differentiation potential of cell sources, including fibrocartilage generation, were comparatively evaluated. To determine the capability of fibrocartilage generation, cultured cell sheets were rolled up to produce cable-form tissue and subjected to chondrogenic induction in the presence or absence of static tension.

resultsAlthough SvMSCs showed superior cell growth characteristics during

conclusionsWhile SvMSCs produced fibrous tissue during default

Indexed as

ChondrocytesMeniscusAnimalsChondrogenesisFibrocartilageMultipotent Stem CellsRabbitschondrocytesfibrocartilagemeniscussynovial MSCstissue engineering

Identifiers

PMID32748647
PMCPMC8804725
OpenAlexW3047602345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.