Trial reportAnnals of clinical and translational neurology2020
Retraining and control therapy for pediatric psychogenic non-epileptic seizures.
Trial report in Annals of clinical and translational neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Systematic review of assessment instruments measuring outcomes in psychological interventions for pediatric functional neurological disorders.Journal of pediatric psychology · 2025Pooled it
- Sense of control, selective attention, cognitive inhibition, and psychosocial outcomes after Retraining and Control Therapy (ReACT) in pediatric functional seizures.Epilepsy & behavior : E&B · 2023Trial
- Treatment of Functional Neurological Disorders.Journal of clinical neurology (Seoul, Korea) · 2026Review
- Current Mental Health Treatment Practices for Functional Neurological Disorders (FND): A Provider Survey.Brain and behavior · 2026Article
- Treating CRPS and FNSD in an Adolescent: A Case Study.Journal of clinical psychology in medical settings · 2026Article
- Pain-related disability in functional neurological disorder (FND): the role of pain intensity and psychological factors.Journal of neurology · 2026Article
- Using a community-based online incentivized survey to describe the healthcare and school-based care of adolescents with functional seizures.Epilepsy & behavior : E&B · 2025Article
- Functional neurological disorder: Practical management.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Telehealth provision of Retraining and Control Therapy (ReACT) on cognitive and biopsychosocial functioning in pediatric functional neurological disorder.Journal of psychosomatic research · 2025Observational
- Retraining and control therapy: sense of control and catastrophic symptom expectations as targets of a cognitive behavioral treatment for pediatric functional seizures.Frontiers in psychiatry · 2025Article
- The adjunct role of pharmacotherapy in multimodal treatment of paediatric functional neurological disorder.Frontiers in psychiatry · 2025Article
- Primum non nocere: Endotracheal Intubation for Prolonged Functional/Dissociative Seizures in an Adolescent.Journal of Brown hospital medicine · 2025Article
- The Children's Somatic Symptoms Inventory-8: Psychometric Properties of a Brief Measure of Somatic Distress.Children (Basel, Switzerland) · 2024Article
- Adolescents' qualitative expressions of functional seizure illness representation.Journal of adolescence · 2024Article
- Neurometabolic alterations in children and adolescents with functional neurological disorder.NeuroImage. Clinical · 2024Article
- Optimizing outcomes when treating functional neurological disorder in acute care settings: case reports depicting the value of diagnostic precision and timely and appropriate psychological interventions using an interdisciplinary framework.Frontiers in psychiatry · 2024Article
- Illness-Promoting Psychological Processes in Children and Adolescents with Functional Neurological Disorder.Children (Basel, Switzerland) · 2023Article
- Adolescents' Perceptions of Functional Seizure Self-Management Strategies, Facilitators, and Barriers in the School Environment.Journal of psychosocial nursing and mental health services · 2023Article
- Treatment Provided in Children and Adolescents with Functional Seizures-A Danish Nationwide Cohort.Children (Basel, Switzerland) · 2023Article
- Functional Neurological Disorder-Old Problem New Perspective.International journal of environmental research and public health · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveOur aim was to conduct a pilot randomized controlled trial of a novel cognitive behaviorally based intervention for pediatric PNES called Retraining and Control Therapy (ReACT).
methodsParticipants were randomized to receive either eight sessions of ReACT or supportive therapy, and participants completed follow-up visits at 7- and 60-days posttreatment. The primary outcome measure was PNES frequency at 7-days posttreatment. Eligibility criteria included children with video-EEG confirmed PNES and participant/parent or guardian willingness to participate in treatment. Exclusion criteria included substance use, psychosis, and severe intellectual disability. Forty-two patients were assessed for eligibility and 32 were randomized. ReACT aimed to retrain classically conditioned, involuntary PNES by targeting catastrophic symptom expectations and a low sense of control over symptoms using principles of habit reversal. Supportive therapy was based on the assumption that relief from stress or problems can be achieved by discussion with a therapist.
resultsTwenty-nine participants (M
interpretationReACT resulted in significantly greater PNES reduction than supportive therapy, with 100% of patients experiencing no PNES in 7 days after ReACT. Additionally, 82% remained PNES-free for 60 days after ReACT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.