Evidence map›Paper›PMID 32748306›Full record

ArticleJournal of assisted reproduction and genetics2020

Cryopreservation and IVF in the time of Covid-19: what is the best good tissue practice (GTP)?

Kimball O Pomeroy, Mitchel C Schiewe

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. ESHRE recommendations on Good Practice in the IVF laboratory†.Human reproduction (Oxford, England) · 2026
    Guideline
  2. Impact of COVID-19 on fertility and assisted reproductive technology (ART): a systematic review.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Pooled it
  3. Review
  4. Risk of contamination with SARS-CoV-2 in ART.Human reproduction (Oxford, England) · 2022
    Article
  5. Reply: Risk of contamination with SARS-CoV-2 in ART.Human reproduction (Oxford, England) · 2022
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kimball O PomeroyThe World Egg Bank, Phoenix, AZ, 85020, USA. kopomeroy@gmail.com.ORCID http://orcid.org/0000-0002-7661-707X
Mitchel C SchieweOvation Fertility, Newport Beach, CA, 92663, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Examine good tissue practices as relates to in vitro fertilization, biopsying, and vitrificationto compare current knowledge of ova, sperm, and embryos as vectors for disease transmission as it relates to our current knowledge regarding the SARS-CoV-2 virus.Unknown risks relating to the SARS-CoV-2 virus and sperm, ova, and embryos necessitate a reexamining of how human IVF is performed. Over the last decade, improvements in cryosurvival and live birth outcomes have been associated with zona pellucida breaching procedures (e.g., blastocyst collapsing and biopsying). In turn, today embryos are generally no longer protected by an intact zona pellucida when vitrified and in cryostorage. Additionally, high security storage containers have proven to be resilient to potential cross-contamination and reliable for routine human sperm freezing and embryo vitrification.Several options to current IVF practices are presented that can effectively mitigate the risks of cross-contamination and infection due to the current Covid-19 pandemic or other viral exposures. The question remains; is heightened security and change warranted where the risks of disease transmission likely remain negligible?

Indexed as

Fertilization in VitroPandemicsBetacoronavirusBlastocystCoronavirus InfectionsCOVID-19CryopreservationEmbryo Culture TechniquesEmbryo, MammalianEmbryo TransferFemaleHumansLive BirthOocytesPneumonia, ViralPregnancyCovid-19Cross-contaminationGood tissue practicesIVF laboratoriesSARS-CoV-2

Identifiers

PMID32748306
PMCPMC7398282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.