Evidence map›Paper›PMID 32748018›Full record

ArticlePflugers Archiv : European journal of physiology2020

Preclinical pharmacological in vitro investigations on low chloride conductance myotonia: effects of potassium regulation.

Kerstin Hoppe, Sunisa Chaiklieng, Frank Lehmann-Horn, Karin Jurkat-Rott, Scott Wearing, Werner Klingler

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pharmacological therapy of non-dystrophic myotonias.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Kerstin HoppeDepartment of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. Hoppekerstinmed@t-online.de.ORCID 0000-0002-5789-7926
Sunisa ChaikliengDivision of Neurophysiology in the Center of Rare Diseases, Ulm University, Albert Einstein Allee 23, 89081, Ulm, Germany.
Frank Lehmann-HornDepartment of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital of Wuerzburg, Oberduerrbacher Str. 6, 97080, Wuerzburg, Germany.
Karin Jurkat-RottUniverstiy Medical Center Ulm, Division of Experimental Anesthesiology, Albert-Einstein-Allee 23, 89081, Ullm, Germany.
Scott WearingInstitute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059, Australia.
Werner KlinglerInstitute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059, Australia.
Queensland University of Technology · AUGoethe University Frankfurt · DEKhon Kaen University · THUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In myotonia, reduced Cl

Indexed as

AnimalsChloride ChannelsChloridesKCNQ Potassium ChannelsLarge-Conductance Calcium-Activated Potassium ChannelsMaleMembrane PotentialsMiceMuscle ContractionMutationMyotonia CongenitaPotassiumPotassium Channel BlockersChloride ChannelsChloridesCLC-1 channelKCNQ Potassium ChannelsLarge-Conductance Calcium-Activated Potassium ChannelsPotassiumPotassium Channel BlockersBK channelKCNQ5 channelMyotonia congenitaWarm-up phenomena

Identifiers

PMID32748018
OpenAlexW3048048353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.